Case Report
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Jul 14, 2020; 9(1): 1-6
Published online Jul 14, 2020. doi: 10.5409/wjcp.v9.i1.1
Acute lymphoblastic leukemia in a β-thalassemia intermedia child: A case report
Laila M Sherief, Esmael Goneim, Naglaa M Kamal, Amr Ibraheim, Fuad Alsofiani, Abdulraouf Alawur
Laila M Sherief, Department of Pediatric Hematology and Oncology, Faculty of Medicine, Zagazig University, Zagazig 44511, Egypt
Laila M Sherief, Amr Ibraheim, Department of Pediatrics, Faculty of Medicine, Zagazig University, Zagazig 44511, Egypt
Esmael Goneim, Department of Pediatric Oncology, Tanta Cancer Institute, Tanta 00202, Egypt
Naglaa M Kamal, Department of Pediatrics and Pediatric Hepatology, Faculty of Medicine, Cairo University, Cairo 21121, Egypt
Naglaa M Kamal, Fuad Alsofiani, Department of Pediatrics, Alhada Armed Forces Hospital, Taif 00966, Saudi Arabia
Author contributions: Sherief LM was involved in conceptualization, data curation, investigation, project administration, supervision, validation, visualization, writing review and editing; Goneim I and Ibraheim A performed data curation; Kamal NM was involved in literature review, writing-original draft, writing review and editing; Alsofiani F and Alawur A performed literature review and wrote the original draft; All authors read and approved the final manuscript.
Informed consent statement: Written informed consent in the patient’s native language was obtained from her father.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Naglaa M Kamal, MD, Full Professor, Department of Pediatrics and Pediatric Hepatology, Faculty of Medicine, Cairo University, Kasralainy, Cairo 21121, Egypt. nagla.kamal@kasralainy.edu.eg
Received: January 17, 2020
Peer-review started: January 17, 2020
First decision: April 18, 2020
Revised: May 9, 2020
Accepted: June 10, 2020
Article in press: June 10, 2020
Published online: July 14, 2020
Core Tip

Core Tip: Cases of malignancies in patients of β-thalassemia major have been reported. However, rare cases have been reported for malignancies in patients of β-thalassemia-intermedia as it is a non-transfusion dependent anemia. Physicians should have high index of suspicion to diagnose malignancies in patients with β-thalassemia-intermedia.