Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. May 8, 2018; 7(2): 67-74
Published online May 8, 2018. doi: 10.5409/wjcp.v7.i2.67
Is obesity related to the lung function of non-asthmatic children?
Andrew Fretzayas, Maria Moustaki, Ioanna Loukou, Konstantinos Douros
Andrew Fretzayas, School of Medicine, University of Athens, Athens 11527, Greece
Andrew Fretzayas, Department of Pediatrics, Athens Medical Center, Athens University Medical School, Maroussi 15125, Greece
Maria Moustaki, Ioanna Loukou, Department of Cystic Fibrosis, “Agia Sofia”, Children’s Hospital, Athens 11527, Greece
Konstantinos Douros, Respiratory Unit, Third Department of Pediatrics, Athens University Medical School, “Attikon” University Hospital, Haidari 15125, Greece
Author contributions: All authors contributed equally to this paper.
Conflict-of-interest statement: Dr. Moustaki has nothing to disclose.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Andrew Fretzayas, MD, PhD, Professor of Pediatrics, Department of Pediatrics, Athens Medical Center, Athens University Medical School, 5-7 Distomou Str, Maroussi 15125, Greece.
Telephone: +30-210-6157269 Fax: +30-210-6862376
Received: February 12, 2018
Peer-review started: February 12, 2018
First decision: March 2, 2018
Revised: March 12, 2018
Accepted: April 11, 2018
Article in press: April 11, 2018
Published online: May 8, 2018
Core Tip

Core tip: We herein present an overview of the existing studies regarding the influence of excess weight on static and dynamic volumes of lung function in otherwise healthy children and adolescents. Although the existing data, are to some extent, conflicting, it seems that in this age group, obesity is correlated to a significant, though not necessarily clinically important, decrease of forced expiratory volume in 1 s/forced vital capacity ratio and a reduction of functional residual capacity. These observations are of clinical relevance, as they may be the origin of respiratory problems in adulthood, especially if obesity persists till then.