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World J Clin Pediatr. Feb 8, 2018; 7(1): 27-35
Published online Feb 8, 2018. doi: 10.5409/wjcp.v7.i1.27
Controversies in diagnosis and management of Kawasaki disease
Rakesh Kumar Pilania, Dharmagat Bhattarai, Surjit Singh
Rakesh Kumar Pilania, Dharmagat Bhattarai, Surjit Singh, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, India
Author contributions: Pilania RK and Bhattarai D wrote the first draft of the manuscript; Singh S reviewed the draft, made changes and completed the final version; all authors approved the submitted version.
Conflict-of-interest statement: None.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Surjit Singh, FRCP (C), MBBS, MD, FAMS, Professor, Department of Pediatrics, Advanced Pediatrics Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Sector 12, Chandigarh 160012, India.
Telephone: +91-987-2283832
Received: October 28, 2017
Peer-review started: October 29, 2017
First decision: December 8, 2017
Revised: December 13, 2017
Accepted: December 28, 2017
Article in press: December 28, 2017
Published online: February 8, 2018
Core Tip

Core tip: The diagnosis of Kawasaki disease poses several challenges for the treating pediatricians as it is based on a set of criteria that are entirely clinical. To further complicate matters, several children present with incomplete and atypical forms of the disease. It is known that children with incomplete and atypical Kawasaki disease do not have milder form of the disease, rather the rate of coronary and non-coronary complications may even be higher in these subgroups as the diagnosis often gets delayed. While intravenous immunoglobulin remains the cornerstone of management, several children require additional form of therapy thereby further challenging the clinical skills and judgment of the pediatricians.