Published online Feb 8, 2016. doi: 10.5409/wjcp.v5.i1.63
Peer-review started: July 31, 2015
First decision: September 27, 2015
Revised: October 17, 2015
Accepted: December 18, 2015
Article in press: December 21, 2015
Published online: February 8, 2016
Core tip: There are several methods allowing for the screening of obstructive sleep apnea (OSA) patients in a large scale, either in the field of molecular diagnosis or in the field of microelectronics Miniaturization technology as well as advances in wireless devices connectivity and data processing allows for more affordable, convenient and reliable recording of parameters such as oxygen saturation, actigraphy and others. In addition, advances in molecular biology allows for the detection of genetic and non-genetic biomarkers of sleep apnea. However the aforementioned markers and their combinations remain to be validated. Until then polysomnography is considered the gold standard for the diagnosis of OSA.