Field of Vision
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Nov 8, 2015; 4(4): 50-54
Published online Nov 8, 2015. doi: 10.5409/wjcp.v4.i4.50
Pediatric obesity prevention: From naïve examination of energy imbalance towards strategies that influence the competition for nutrient resources among tissues
Lynae J Hanks, Tina Simpson, Kenneth McCormick, Krista Casazza
Lynae J Hanks, Department of Kinesiology, University of Montevallo, Montevallo, AL 35115, United States
Tina Simpson, Krista Casazza, Division of General Pediatrics and Adolescent Medicine, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, United States
Kenneth McCormick, Division of Endocrinology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35233, United States
Author contributions: Hanks LJ, Simpson T, McCormick K and Casazza K contributed to writing, editing and revising of this paper.
Conflict-of-interest statement: We, authors declare no conflict of interest regarding our manuscript “Pediatric obesity prevention: From naïve examination of energy imbalance towards strategies that influence the competition for nutrient resources among tissues”.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Krista Casazza, PhD, RD, LD, Associate Professor, Division of General Pediatrics and Adolescent Medicine, Department of Pediatrics, University of Alabama at Birmingham,1601 5th Ave S, CPPI 310, Birmingham, AL 35223, United States. kcasazza@peds.uab.edu
Telephone: +1-205-6386856 Fax: +1-205-9756503
Received: May 28, 2015
Peer-review started: June 1, 2015
First decision: August 14, 2015
Revised: September 14, 2015
Accepted: October 16, 2015
Article in press: October 19, 2015
Published online: November 8, 2015
Processing time: 166 Days and 11.7 Hours
Core Tip

Core tip: As obesity-related recommendations stand today, most are unproven and ineffective. While energy balance is an integral component, the etiology of pediatric obesity is a consequence of adipocytes “out competing” other cell types (e.g., myocytes, osteocytes, hepatocytes) for energy. The cumulative effect of fat storage, energetically less costly is at the expense of optimal development of other tissues. The out-competition, due to hyperplasia and hypertrophy of adipocytes impairs physiologic pathways producing metabolically compromised obese children irreversible with “simple” energy balance paradigms. Via the activation of endocrine and paracrine effects of the musculoskeletal system, resistance training may be an effective strategy to improve health independent of initial weight loss. However, forced stress on the system is requisite (e.g., resistance training). Resistance training induces systemic anabolism and enhances nutrient delivery and utilization, which are integral in optimizing metabolic control and body composition during growth and development, and in turn overall lifelong health.