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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Nov 8, 2015; 4(4): 135-142
Published online Nov 8, 2015. doi: 10.5409/wjcp.v4.i4.135
Published online Nov 8, 2015. doi: 10.5409/wjcp.v4.i4.135
Use of corticosteroids during acute phase of Kawasaki disease
Jeong Jin Yu, Department of Pediatrics Cardiology, College of Medicine, Ulsan University, Ulsan 680-749, South Korea
Jeong Jin Yu, Department of Pediatrics, Asan Medical Center, Seoul 138-736, South Korea
Author contributions: Yu JJ solely contributed to this manuscript.
Conflict-of-interest statement: I have no relevant financial relationships to disclose or conflicts of interest to resolve.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jeong Jin Yu, MD, PhD, Department of Pediatrics, Asan Medical Center, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 138-736, South Korea. pediatrist@medimail.co.kr
Telephone: +82-2-30103924 Fax: +82-2-4733725
Received: July 2, 2015
Peer-review started: July 8, 2015
First decision: August 25, 2015
Revised: August 28, 2015
Accepted: October 16, 2015
Article in press: October 19, 2015
Published online: November 8, 2015
Peer-review started: July 8, 2015
First decision: August 25, 2015
Revised: August 28, 2015
Accepted: October 16, 2015
Article in press: October 19, 2015
Published online: November 8, 2015
Core Tip
Core tip: In spite of initial intravenous immunoglobulin (IVIG) treatment, a significant number of patients are unresponsive to it and are at a higher risk for coronary artery lesions. Corticosteroids have been used as a secondary drug or used in combination with IVIG. There are several options of using corticosteroids for the treatment of patients with Kawasaki disease during the acute phase. A thorough review of the use of corticosteroids in acute phase Kawasaki disease was performed in this paper.