Published online Aug 8, 2015. doi: 10.5409/wjcp.v4.i3.41
Peer-review started: March 31, 2015
First decision: May 13, 2015
Revised: May 21, 2015
Accepted: June 18, 2015
Article in press: June 19, 2015
Published online: August 8, 2015
Core tip: Neural tube defects are severe congenital malformations of the central nervous system. The prevalence of these defects in China is among the highest in the world. Low intake of dietary folate is to be blamed. The provision of free-of-charge folic acid supplements to all women who live in rural areas and plan to become pregnant has been implemented since 2009. However, fortification of staple foods with folic acid has not been planned. It is time to consider fortification since many pregnancies are unplanned and therefore it is difficult for a woman to take folic acid supplements from before pregnancy.