Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. May 8, 2015; 4(2): 25-29
Published online May 8, 2015. doi: 10.5409/wjcp.v4.i2.25
Pyuria in patients with Kawasaki disease
Toru Watanabe
Toru Watanabe, Department of Pediatrics, Niigata City General Hospital, Chuo-ku, Niigata City 950-1197, Japan
Author contributions: Watanabe T solely contributed to this paper.
Conflict-of-interest: The author has no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Toru Watanabe, MD, PhD, Department of Pediatrics, Niigata City General Hospital, 463-7 Shumoku, Chuo-ku, Niigata City 950-1197, Japan.
Telephone: +81-25-2815151 Fax: +81-25-2815169
Received: November 19, 2014
Peer-review started: November 20, 2014
First decision: December 26, 2014
Revised: January 8, 2015
Accepted: February 4, 2015
Article in press: February 9, 2015
Published online: May 8, 2015
Core Tip

Core tip: Pyuria is a common feature of patients with Kawasaki disease (KD), occurring in 30%-80% of patients. KD patients with pyuria exhibit more severe inflammatory reactions and may have sub-clinical renal injuries. Pyuria in KD originates from the urethra, the kidney as a result of mild and sub-clinical renal injuries, and/or the bladder due to cystitis. Pyuria is not always sterile in KD, but can result from a urinary tract infection (UTI). Because some KD patients with UTIs have urinary tract abnormalities, a complete UTI workup including renal ultrasound, voiding cystourethrogram and/or dimercaptosuccinic acid renal scan is recommended in KD patients with UTIs.