Observational Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Pediatr. Sep 9, 2025; 14(3): 106763
Published online Sep 9, 2025. doi: 10.5409/wjcp.v14.i3.106763
Effect of oral food challenge on quality of life and family activities in children with IgE-mediated food allergies
Azwin Mengindra Putera, Irwanto Irwanto
Azwin Mengindra Putera, Irwanto Irwanto, Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya 60132, Jawa Timur, Indonesia
Azwin Mengindra Putera, Division of Allergy Immunology and Rheumatology, Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya 60286, Jawa Timur, Indonesia
Irwanto Irwanto, Division of Growth and Development, Department of Child Health, Dr. Soetomo General Academic Hospital, Surabaya 60286, Jawa Timur, Indonesia
Author contributions: Putera AM, Irwanto contributed to conceptualization and design; Putera AM contributed to material preparation, data acquisition, and analysis; all author authors contributed to writing-draft manuscript and writing-revision and approved to submit the final version.
Institutional review board statement: The study was protocol approved by the ethical committee team at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia (No. 0581/LOE/301.4.2/IX/2021).
Informed consent statement: Informed consent was obtained from all participants involved in the study.
Conflict-of-interest statement: All authors declare that they have no conflict of interest.
STROBE statement: The authors read the STROBE Statement checklist of items, and the manuscript was prepared and revised according to it.
Data sharing statement: The datasets generated during and/or analyzed during the current study are available from the corresponding author upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Azwin Mengindra Putera, PhD, Associate Professor, Department of Child Health, Faculty of Medicine, Universitas Airlangga, Jl. Mayjend Prof. Dr. Moestopo No. 47, Pacar Kembang, Tambaksari, Surabaya 60132, Jawa Timur, Indonesia. azwin-m-p@fk.unair.ac.id
Received: March 7, 2025
Revised: April 14, 2025
Accepted: May 21, 2025
Published online: September 9, 2025
Processing time: 102 Days and 4.5 Hours
Core Tip

Core Tip: Oral food challenge (OFC) is the gold standard for diagnosing food allergy (FA), and diagnosis of FA can affect quality of life (QoL) and family activities. Therefore, OFC can contribute to QoL, including definitive diagnosis, identifying disease severity, reducing anxiety, expanding the diet, increasing activities outside the home, and creating an adaptive environment in which the contributions are also associated with family activities. The crucial suggestion from the study are to create a safe environment for children with FA, in which the teacher and caretaker must improve their knowledge of FA, including its clinical manifestation, anaphylaxis, and administration of adrenaline auto-injection when needed immediately.