Makarova E, Khabirova A, Volkova N, Gabrusskaya T, Ulanova N, Sakhno L, Revnova M, Kostik M. Vaccination coverage in children with juvenile idiopathic arthritis, inflammatory bowel diseases, and healthy peers: Cross-sectional electronic survey data. World J Clin Pediatr 2023; 12(2): 45-56 [PMID: 37034429 DOI: 10.5409/wjcp.v12.i2.45]
Corresponding Author of This Article
Mikhail Kostik, MD, PhD, Full Professor, Professor, Department of Hospital Pediatrics, Saint-Petersburg State Pediatric Medical University, Lytovskaya 2, Saint-Petersburg 194100, Russia. kost-mikhail@yandex.ru
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Cohort Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Pediatr. Mar 9, 2023; 12(2): 45-56 Published online Mar 9, 2023. doi: 10.5409/wjcp.v12.i2.45
Vaccination coverage in children with juvenile idiopathic arthritis, inflammatory bowel diseases, and healthy peers: Cross-sectional electronic survey data
Elizaveta Makarova, Larisa Sakhno, Maria Revnova, Department of Polyclinic Pediatrics, Saint-Petersburg State Pediatric Medical University, Saint-Petersburg 194100, Russia
Aygul Khabirova, Mikhail Kostik, Department of Hospital Pediatrics, Saint-Petersburg State Pediatric Medical University, Saint-Petersburg 194100, Russia
Natalia Volkova, Tatiana Gabrusskaya, Natalia Ulanova, Department of Pediatric GI, Saint-Petersburg State Pediatric Medical University, Saint-Petersburg 194100, Russia
Author contributions: All authors were involved in the conception, drafting, and critical revision of the article, read and approved the final manuscript.
Institutional review board statement: The study was approved by the Ethical Committee of the Saint-Petersburg State Pediatric Medical University (Protocol №3 from 01/03/2021). There were no violations of patients' rights according to the Declaration of Helsinki. The study was completely anonymous.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: All authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Data sharing statement: The original contributions presented in the study are included in the article/supplementary material, further inquiries can be directed to the corresponding author/s.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Mikhail Kostik, MD, PhD, Full Professor, Professor, Department of Hospital Pediatrics, Saint-Petersburg State Pediatric Medical University, Lytovskaya 2, Saint-Petersburg 194100, Russia. kost-mikhail@yandex.ru
Received: December 4, 2022 Peer-review started: December 4, 2022 First decision: January 9, 2023 Revised: January 25, 2023 Accepted: February 13, 2023 Article in press: February 13, 2023 Published online: March 9, 2023
ARTICLE HIGHLIGHTS
Research background
Patients with immune-mediated diseases have incomplete vaccination.
Research motivation
There are no previous studies about parental view of the reasons of incomplete vaccination.
Research objectives
To evaluate the parental view about possible reasons of incomplete vaccination.
Research methods
An electronic survey for parents of immune-mediated disease patients and healthy controls was created and disseminated. The analysis of response was done.
Research results
Lower vaccine coverage in immune mediated patients was detected, compared to healthy controls. Medical conditions were the main medical reasons for incomplete vaccination in juvenile idiopathic arthritis (JIA) and inflammatory bowel disease (IBD). Less rate of vaccine-associated reactions was reported in IBD. Pediatric rheumatologists rarely explain the safety and benefits of vaccinations. Pediatric gastroenterology physicians frequently checked anti-vaccine antibodies and recommend more supplementary vaccines.
Research conclusions
Children with immune-mediated disease (IBD and JIA) have incomplete vaccination. The encouraging role of physicians and lack of discussion about the vaccines from physicians are factors, influencing completeness of the vaccination.
Research perspectives
Future studies on the effectiveness of educational programs supporting vaccinations may be planned.
