World J Clin Pediatr. Sep 9, 2025; 14(3): 107538 Published online Sep 9, 2025. doi: 10.5409/wjcp.v14.i3.107538
Childhood gastroesophageal reflux disease
Anand Pandey
Anand Pandey, Department of Pediatric Surgery, King George's Medical University, Lucknow 226003, Uttar Pradesh, India
Author contributions: Pandey A was responsible for the concept, preparation, review of the literature, preparation of the first and final draft of the manuscript.
Conflict-of-interest statement: The author declares that he has no conflicts of interest relevant to this manuscript.
Corresponding author: Anand Pandey, Professor, Department of Pediatric Surgery, King George's Medical University, Chowk, Lucknow 226003, Uttar Pradesh, India. dranand27@rediffmail.com
Received: March 26, 2025 Revised: April 16, 2025 Accepted: May 7, 2025 Published online: September 9, 2025 Processing time: 83 Days and 2.2 Hours
Abstract
The diagnosis of gastroesophageal reflux (GERD) in children is a complex and challenging task that requires meticulous attention to detail and a deep understanding of pediatric physiology. It is absolutely crucial to distinguish between the benign chalasia of infancy and the more serious pathologic GERD. Recent advancements have shown that Combined Multichannel Intraluminal Impedance and pondus hydrogenii measurement offer superior diagnostic accuracy. The role of nuclear scans in diagnosing GERD remains an area of ongoing research. The management of GERD in children follows a stepwise approach, starting with medical therapy and progressing to surgical intervention if necessary.
Core Tip: Gastroesophageal reflux disease in children is an important clinical condition. It needs to be differentiated from benign causes or reflux. Understanding its physiology and need for either medical or surgical management is of utmost importance.
