Elghoudi A, Zourob D, Al Atrash E, Alshamsi F, Alkatheeri M, Narchi H, Bitar R. Evolving strategies: Enhancements in managing eosinophilic esophagitis in pediatric patients. World J Clin Pediatr 2024; 13(1): 89580 [PMID: 38596434 DOI: 10.5409/wjcp.v13.i1.89580]
Corresponding Author of This Article
Rana Bitar, MBBS, Adjunct Associate Professor, Division of Pediatric Gastroenterology, Sheikh Khalifa Medical City, Al Karamah St., Abu Dhabi, United Arab Emirates. rahmad@seha.ae
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Pediatr. Mar 9, 2024; 13(1): 89580 Published online Mar 9, 2024. doi: 10.5409/wjcp.v13.i1.89580
Evolving strategies: Enhancements in managing eosinophilic esophagitis in pediatric patients
Ahmed Elghoudi, Doaa Zourob, Eman Al Atrash, Fatima Alshamsi, Manal Alkatheeri, Hassib Narchi, Rana Bitar
Ahmed Elghoudi, Department of Pediatric, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates
Doaa Zourob, Eman Al Atrash, Manal Alkatheeri, Rana Bitar, Division of Pediatric Gastroenterology, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates
Fatima Alshamsi, Pediatric Residency Program, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates
Hassib Narchi, College of Medicine and Health Sciences, United Arab Emirates University, Alain, Abu Dhabi, United Arab Emirates
Author contributions: Elghoudi A and Bitar R made substantial contributions to the conception and design of the work, interpretation of data, drafting, writing and revising the manuscript critically for important intellectual content and approved the final version to be published, and agrees to be accountable for all aspects of the work; Zourob A, Al Atrash E, Alshamsi F, Alkatheeri M, and Narchi H made substantial contributions to the design of the work, acquisition and interpretation of data and revising the manuscript critically for important intellectual content, and approved the final version to be published and agree to be accountable for all aspects of the work.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Rana Bitar, MBBS, Adjunct Associate Professor, Division of Pediatric Gastroenterology, Sheikh Khalifa Medical City, Al Karamah St., Abu Dhabi, United Arab Emirates. rahmad@seha.ae
Received: November 27, 2023 Peer-review started: November 27, 2023 First decision: December 17, 2023 Revised: December 26, 2023 Accepted: January 16, 2024 Article in press: January 16, 2024 Published online: March 9, 2024
Abstract
Eosinophilic esophagitis is a newly recognized disease first described about 50 years ago. The definition, diagnosis, and management have evolved with new published consensus guidelines and newly approved treatment available to pediatricians, enabling a better understanding of this disease and more targeted treatment for patients. We describe the definition, presentation, and diagnosis of eosinophilic esophagitis including management, challenges, and future directions in children. The definition, diagnosis, and management of eosinophilic esophagitis have evolved over the last 50 years. Consensus guidelines and newly approved biologic treatment have enabled pediatricians to better understand this disease and allow for more targeted treatment for patients. We describe the definition, presentation, diagnosis, management, and treatment in addition to the challenges and future directions of eosinophilic esophagitis management in children.
Core Tip: Eosinophilic esophagitis is a newly recognized disease described in the last 50 years. The definition, diagnosis, and management have evolved with new guidelines and medications available to allow for better understanding and treatment of pediatric patients. We describe the definition, presentation, diagnosis, and management including new biological treatment, long-term follow-up and the challenges of eosinophilic esophagitis in children. We discuss new management strategies and new future directions of monitoring eosinophilic esophagitis in children.
