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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Angina bullosa hemorrhagica an enigmatic oral disease
Javier Alberdi-Navarro, María Luisa Gainza-Cirauqui, María Prieto-Elías, José Manuel Aguirre-Urizar, Oral Medicine and Oral and Maxillofacial Pathology Units, Dental Clinic Service, Master in Oral Pathology, Department of Stomatology II, UFI 11/25, University of the Basque Country/EHU, 48950 Leioa, Spain
María Luisa Gainza-Cirauqui, Department of Dental Surgery, Faculty of Dental Surgery, University of Malta, 2080 Msida, Malta
Author contributions: Alberdi-Navarro J and Aguirre-Urizar JM designed study; Alberdi-Navarro J, Gainza-Cirauqui ML and Prieto-Elías M contributed to bibliographic research; Alberdi-Navarro J and Prieto-Elías M drafted paper; Gainza-Cirauqui ML and Aguirre-Urizar JM contributed to critical review.
Conflict-of-interest: The authors have no conflict of interest to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: José Manuel Aguirre-Urizar, PhD, Oral Medicine and Oral and Maxillofacial Pathology Units, Dental Clinic Service, Master in Oral Pathology, Department of Stomatology II, UFI 11/25, University of the Basque Country/EHU, Barrio Sarrera s/n, 48950 Leioa, Spain. josemanuel.aguirre@ehu.es
Telephone: +34-94-6015711
Received: October 15, 2014
Peer-review started: October 20, 2014
First decision: December 17, 2014
Revised: December 28, 2014
Accepted: January 9, 2015
Article in press: January 12, 2015
Published online: February 20, 2015
Peer-review started: October 20, 2014
First decision: December 17, 2014
Revised: December 28, 2014
Accepted: January 9, 2015
Article in press: January 12, 2015
Published online: February 20, 2015
Core Tip
Core tip: Although it is an uncommon disease, the angina bullosa hemorrhagica should be considered in the differential diagnosis of oral vesiculo-bullous processes. Acknowledging this entity will help in differentiating it from important mucocutaneous and hematological diseases such as pemphigus vulgaris, mucous membrane pemphigoid or coagulation disorders. In this review we analyze the main etiopathogenic, clinicopathological, diagnostic and therapeutic aspects of this enigmatic oral condition.