Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stomatol. May 20, 2015; 4(2): 87-95
Published online May 20, 2015. doi: 10.5321/wjs.v4.i2.87
Treatment of mouth and jaw diseases with intralesional steroid injection
Alparslan Esen, Kubilay Işık, Doğan Dolanmaz
Alparslan Esen, Kubilay Işık, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Necmettin Erbakan University, 42050 Konya, Turkey
Doğan Dolanmaz, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Selcuk University, 42250 Konya, Turkey
Author contributions: All authors contributed equally to this work but especially Esen A wrote the manuscript; Esen A and Işık K contributed to reviewing the literature; Dolanmaz D designed the aim of the editorial.
Conflict-of-interest: Authors notify no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Alparslan Esen, DDS, PhD, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Necmettin Erbakan University, Ankara Cd. No: 74/A, Karatay, 42050 Konya, Turkey.
Telephone: +90-332-2200026 Fax: +90-332-2200045
Received: September 3, 2014
Peer-review started: September 4, 2014
First decision: November 27, 2014
Revised: December 30, 2014
Accepted: January 15, 2015
Article in press: January 17, 2015
Published online: May 20, 2015

Many lesions of the oral region are treated with surgical methods such as curettage and resection. Chemotherapy and radiation therapy with or without surgical intervention can be used as an adjunct in some cases. Intralesional steroid injection is a conservative procedure which is already used in various regions of the body and joints. This technique is used also for a number of mouth and jaw lesions. Localized langerhans cell histiocytosis, central giant cell granuloma, oral submucous fibrosis, oral lichen planus, lichen sclerosus of the oral mucosa, lymphatic malformations and orofacial granulomatosis can be considered among these diseases. The purpose of this review is to investigate the effects of intralesional steroid injections in the treatment of oral diseases.

Keywords: Intralesional injections, Steroids, Langerhans Cell histiocytosis, Giant cell granuloma, Oral submucous fibrosis, Oral lichen planus, Orofacial granulomatosis

Core tip: Intralesional steroid injections are often used in the lesion occurred in oral and maxillofacial region in recent years. Especially in large lesions, it can be applied as an alternative or adjunct to surgical procedures. It is an effective treatment method, because, without the need for major surgical procedures and providing patient comfort.