Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stomatol. May 20, 2015; 4(2): 39-55
Published online May 20, 2015. doi: 10.5321/wjs.v4.i2.39
Platelet preparations in dentistry: How? Why? Where? When?
Luigi Fabrizio Rodella, Veronica Bonazza
Luigi Fabrizio Rodella, Veronica Bonazza, Department of Clinical and Experimental Sciences, Division of Anatomy and Physiopathology, University of Brescia, 25123 Brescia, Italy
Author contributions: Both authors contributed to this mansucript.
Conflict-of-interest: Dr. Rodella and Dr. Bonazza declare that there is no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Luigi Fabrizio Rodella, MD, Department of Clinical and Experimental Sciences, Division of Anatomy and Physiopathology, University of Brescia, V.le Europa 11, 25123 Brescia, Italy.
Telephone: +39-030-3717485 Fax: +39-030-3717486
Received: February 13, 2015
Peer-review started: February 22, 2015
First decision: March 20, 2015
Revised: April 10, 2015
Accepted: April 28, 2015
Article in press: May 4, 2015
Published online: May 20, 2015

The aim of this article is to review the outcomes of platelet preparations in dentistry. A structured electronic search discovered 348 articles, which described the use of autologous platelet concentrates with a relevance to clinical dentistry. Among these articles, 220 articles investigated platelet rich plasma, 99 investigated platelet rich fibrin, 22 investigated plasma rich in growth factors and 7 investigated the use of concentrated growth factors. Several studies reported beneficial treament outcomes in terms of enhanced bone and soft tissue regeneration.

Keywords: Platelet concentrates, Platelet rich plasma, Platelet rich fibrin, Concentrated growth factors, Growth factors, Dentistry, Plasma rich in growth factors

Core tip: Autologous platelet concentrates (platelet-rich plasma, platelet rich fibrin, plasma rich in growth factors, concentrated growth factor), are blood derivatives, prepared from patient's own blood, reach in platelets, growth factors and cytokines, which can be used to promote guided tissue regeneration in dentistry and oral surgery.