Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Stomatol. May 20, 2015; 4(2): 103-107
Published online May 20, 2015. doi: 10.5321/wjs.v4.i2.103
Oral lichenoid lesion: A review of the literature
Soraya de Mattos Camargo Grossmann, Camila de Nazaré Alves de Oliveira, Giovanna Ribeiro Souto, Caroline Góes, Ricardo Alves Mesquita
Soraya de Mattos Camargo Grossmann, Universidade Vale do Rio Verde, Unincor, Barro Preto, 32600-416 Belo Hozironte/MG, Brazil
Camila de Nazaré Alves de Oliveira, Giovanna Ribeiro Souto, Ricardo Alves Mesquita, Department of the Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Pampulha, 31270-010 Belo Horizonte/MG, Brazil
Caroline Góes, Private Dentistry, 73015-132 Brasília/DF, Brazil
Author contributions: de Oliveira C de NA, Souto GR and Góes C analyzed the literature and wrote the paper; Grossmann S de MC and Mesquita RA designed and prepared the paper.
Supported by Grants from National Council for Scientific Technological Development (CNPq, #309209/2010-2); Mesquita RA is research fellows of CNPq.
Conflict-of-interest: There is not conflict-of-interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Ricardo Alves Mesquita, DDS, PhD, Professor, Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Faculdade de Odontologia, Av. Antônio Carlos, 6627 sala 3204 - Pampulha, 31270-010 Belo Horizonte/MG, Brazil.
Telephone: +55-31-34092499 Fax: +55-31-34092430
Received: December 3, 2014
Peer-review started: December 4, 2014
First decision: January 20, 2015
Revised: January 26, 2015
Accepted: February 10, 2015
Article in press: February 12, 2015
Published online: May 20, 2015

The oral lichenoid lesion (OLL) is response that occurs on the oral mucosa. The OLL include allergic response to the dental materials, drugs, and on graft-vs-host disease (GVHD). OLL to dental material happen when restorative materials, most commonly amalgam, are in direct contact with the mucosa in sensitized individuals. Medications that produce OLL are oral hypoglycemic agents, angiotensin-converting enzyme inhibitors, and nonsteroidal anti-inflammatory agents. GVHD is a complication in bone marrow transplantation and OLL is a common lesion observed in this disease especially in chronic GVHD. The clinical and histological aspects of OLL are similar to oral lichen planus and turn it difficult to make a differential diagnosis. The purpose of this paper is review about OLL related to the dental materials, drug use and GVHD.

Keywords: Oral lichenoid lesion, Lichenoid contact reaction, Lichenoid drug reaction, Lichenoid related to graft-vs-host disease

Core tip: There are various oral manifestations like oral lichen planus. These lesions are related to local or systemic factors and are important in oral diagnosis and patient’s management. Considering the increased of number of these lesion in current moment, we investigated previous publications and aim to present a literature review.