Copyright ©The Author(s) 2017.
World J Respirol. Jul 28, 2017; 7(2): 39-47
Published online Jul 28, 2017. doi: 10.5320/wjr.v7.i2.39
Figure 2
Figure 2 Lung microbiome disturbances following respiratory diseases exacerbations (adapted from Dickson RP 2014). The triggers like virus, allergens, pollutants initiate airway inflammation with activation of alveolar macrophages, neutrophils, eosinophils, dendritic cells, lymphocytes, which alters growth conditions of airway microbiota. Altered growth conditions result in a disturbed microbiome, which promotes further airway inflammation via pathogen-associated molecular patterns and pattern recognition receptor interactions.