Copyright
©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Classical regression equations of spirometric parameters are not applicable for diagnosing spirometric abnormalities in adipotic adults
Kazuhiro Yamaguchi, Takao Tsuji, Department of Respiratory Medicine, Tokyo Medical University, Tokyo 160-0023, Japan
Hisamitsu Omori, Department of Biomedical Laboratory Sciences, Kumamoto University, Kumamoto 860-8556, Japan
Kazutetsu Aoshiba, Department of Respiratory Medicine, Tokyo Medical University, Ibaraki Medical Center, Ibaraki 300-0395, Japan
Author contributions: All authors contributed conception and designation of the study; they contributed acquisition, analysis and interpretation of the data; they expressed the final approval of the version of the article.
Conflict-of-interest statement: The authors have no conflict of interest to declare. There were no supportive foundations to the present study.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kazuhiro Yamaguchi, FCCP, MD, PhD, Professor, Department of Respiratory Medicine, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo 160-0023, Japan. yamaguc@sirius.ocn.ne.jp
Telephone: +81-3-34215402 Fax: +81-3-34215402
Received: July 24, 2018
Peer-review started: July 24, 2018
First decision: August 30, 2018
Revised: September 29, 2018
Accepted: November 13, 2018
Article in press: November 14, 2018
Published online: November 26, 2018
Peer-review started: July 24, 2018
First decision: August 30, 2018
Revised: September 29, 2018
Accepted: November 13, 2018
Article in press: November 14, 2018
Published online: November 26, 2018
Core Tip
Core tip: The impacts of age and a variety of anthropometric factors, including standing height, body weight, and fat fraction body mass, on decision of the spirometric parameters (SPs) differ significantly between non-adipotic adults [i.e., normal body mass index (BMI)] and adipotic adults (i.e., increased BMI). Therefore, if the reference means and lower limits of normal of SPs estimated from the regression equations established for non-adipotic adults are used, substantial errors will emerge while diagnosing the lung function abnormalities in adipotic adults.