Basic Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Respirol. Mar 28, 2016; 6(1): 24-32
Published online Mar 28, 2016. doi: 10.5320/wjr.v6.i1.24
Pulmonary effects of intermittent, seasonal exposure to high concentrations of cotton dust
Masoud Neghab, Esmaeel Soleimani, Morteza Nowroozi-Sarjoeye
Masoud Neghab, Research Center for Health Sciences, Shiraz University of Medical Sciences, Shiraz 71645, Iran
Esmaeel Soleimani, Morteza Nowroozi-Sarjoeye, Student’s Research Committee, School of Health, Shiraz University of Medical Sciences, Shiraz 71645, Iran
Author contributions: Neghab M and Nowroozi-Sarjoye M substantially contributed to the conception and design of the study, acquisition, analysis and interpretation of data; Neghab M, Soleimani E and Nowroozi-Sarjoye M drafted the article and made critical revisions related to the intellectual content of the manuscript, and approved the final version of the article to be published.
Supported by Shiraz University of Medical Sciences, Vice chancellor for research and technology, No. 91-6347.
Institutional review board statement: All participants signed an informed consent form before participation in the study. The protocol of the study was approved by the University Ethics Committee.
Institutional animal care and use committee statement: Not applicable.
Conflict-of-interest statement: No conflict of interest exist whatsoever.
Data sharing statement: The data referred to in this manuscript have been generated solely by the authors. No other party has been involved. Therefore, the issue of data sharing is not applicable here.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Morteza Nowroozi-Sarjoeye, Student’s Research Committee, School of Health, Shiraz University of Medical Sciences, PO Box 111, Shiraz 71645, Iran. nowroozi.morteza@gmail.com
Telephone: +98-713-7251020 Fax: +98-713-7260225
Received: May 23, 2015
Peer-review started: May 23, 2015
First decision: August 14, 2015
Revised: September 9, 2015
Accepted: November 17, 2015
Article in press: November 17, 2015
Published online: March 28, 2016
Core Tip

Core tip: It is not known whether long term seasonal exposure to high concentrations of cotton dust for a few months per year followed by several months of exposure free period in ginning industry is associated with any pulmonary effects. Findings of the present study indicate that even seasonal exposure to high concentrations of this organic dust is a risk factor for byssinosis manifested by acute partially reversible and chronic irreversible significant decrements in lungs’ functional capacities and increased prevalence of respiratory symptoms.