Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Respirol. Jul 28, 2015; 5(2): 69-77
Published online Jul 28, 2015. doi: 10.5320/wjr.v5.i2.69
Published online Jul 28, 2015. doi: 10.5320/wjr.v5.i2.69
Post splenectomy related pulmonary hypertension
Atul V Palkar, Sameer Verma, Asma Iftikhar, Edmund J Miller, Arunabh Talwar, Department of Pulmonary, Critical Care and Sleep Medicine, North Shore - LIJ Health System, New York, NY 11040, United States\
Abhinav Agrawal, Department of Medicine, Monmouth Medical Center, Long Branch, NJ 07740, United States
Sameer Verma, Asma Iftikhar, Edmund J Miller, Arunabh Talwar, Feinstein Institute of Medical Research, Center for Heart and Lung Research, New York, NY 11030, United States
Author contributions: All the authors equally contributed to this work.
Supported by NIH 1R01HL111469 and ECRIP Fellowship.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Arunabh Talwar, MD, FCCP, Department of Pulmonary, Critical Care and Sleep Medicine, North Shore - LIJ Health System, 410 Lakeville Rd. Suite 107 New Hyde Park, New York, NY 11040, United States. arunabhtalwar1@gmail.com
Telephone: +1-516-4655400 Fax: +1-516-4655454
Received: January 29, 2015
Peer-review started: January 30, 2015
First decision: March 6, 2015
Revised: March 25, 2015
Accepted: May 8, 2015
Article in press: May 11, 2015
Published online: July 28, 2015
Peer-review started: January 30, 2015
First decision: March 6, 2015
Revised: March 25, 2015
Accepted: May 8, 2015
Article in press: May 11, 2015
Published online: July 28, 2015
Core Tip
Core tip: Pulmonary hypertension is an often under-recognized non-infectious complication after splenectomy. The mechanisms for the development of pulmonary hypertension in this setting are multifactorial and are not clearly elucidated. We attempt to outline and highlight the current evidence behind these proposed mechanisms of post splenectomy related pulmonary hypertension.