Published online Mar 28, 2015. doi: 10.5320/wjr.v5.i1.28
Peer-review started: September 29, 2014
First decision: December 12, 2014
Revised: January 20, 2015
Accepted: February 4, 2015
Article in press: February 5, 2015
Published online: March 28, 2015
Core tip: Gastroesophageal reflux disease is a common gastrointestinal condition in the Western world, but remains challenging to treat. Acid suppression with proton-pump inhibitors substantially improves medical therapy, though it is not successful in all patients. Recently, some studies have shown that inspiratory muscle training increases lower esophageal sphincter pressure in patients with gastroesophageal reflux disease. However, other well-controlled studies are needed to establish if there is a substantial gain and maintenance in pressure, as well as clinical improvement, and to access the influence of inspiratory muscle training in particular group of individuals.