Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Respirol. Nov 5, 2020; 10(2): 11-16
Published online Nov 5, 2020. doi: 10.5320/wjr.v10.i2.11
Personalising exacerbation prediction strategies in chronic obstructive pulmonary disease
Paul R Ellis, Alice M Turner
Paul R Ellis, Alice M Turner, Institute of Applied Health Research, University of Birmingham, Birmingham B15 2TT, United Kingdom
Author contributions: Ellis PR wrote the initial draft manuscript; Turner AM and Ellis PR both contributed to the review and editing of the final manuscript.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Paul R Ellis, MBChB, Research Fellow, Institute of Applied Health Research, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom. p.ellis@bham.ac.uk
Received: April 30, 2020
Peer-review started: April 30, 2020
First decision: July 4, 2020
Revised: August 22, 2020
Accepted: September 8, 2020
Article in press: September 8, 2020
Published online: November 5, 2020
Core Tip

Core Tip: Chronic obstructive pulmonary disease (COPD) patients and the exacerbations they suffer are complex and heterogenous in nature. They should all be treated on an individual basis with detailed clinical history and initial work up to better understand the impact it is having on their life. Careful consideration of the benefits of treatment should be weighed up against the risks of their side effects to ensure the maximum benefit of treatment. Precision medicine is starting to appear in management of COPD, both for acute exacerbations and their prevention.