Antimicrobial potential of Terminalia chebula Retz. fruit extracts against ear pathogens

Table 1 Antibacterial and antiyeast activity of Terminalia chebula fruits extract on ear pathogens

Solvent	Diameter of growth of inhibition zones (mm)
extracts (mg/mL)	Sa	Pm	Pa	Ec	As	Ca
Acetone	31.6a1± 1.522	21.0 ± 1.0	23.6 ± 1.15	19.3 ± 1.52	24.6 ± 0.57	-
Ethanol	27.3 ± 1.15	19.3 ± 1.15	20.6 ± 1.15	15.6 ± 0.57	21.6 ± 1.15	-
Methanol	28.6 ± 0.57	20.6 ± 0.57	22.3 ± 1.52	16.3 ± 1.52	22.3 ± 1.15	-
Hot aqueous	26.3 ± 1.15	17.3 ± 0.57	16.3 ± 1.15	14.3 ± 1.15	18.3 ± 0.57	-
Cold aqueous	25.6 ± 0.57	15.6 ± 1.52	14.6 ± 1.52	13.6 ± 0.57	17.6 ± 1.52	-
Ciplox ear drop	56.3 ± 0.57	46.3 ± 1.52	34.0 ± 1.0	36.3 ± 0.57	32.6 ± 0.57	NT
Kan pip ear drop	26.3 ± 1.52	20.3 ± 0.57	18.3 ± 1.52	23.6 ± 1.15	21.6 ± 1.52	16.3 ± 1.15
Candid ear drop	NT	NT	NT	NT	NT	21.6 ± 0.57

¹Values, including diameter of the well (8 mm), are means of three replicates,

²± SD. The data were analyzed by one way analysis of variance followed by Dunnett’s test.

^aP <0.01 vs positive control. Sa: Staphylococcus aureus; Pm: Proteus mirabilis; Pa: Pseudomonas aeruginosa; Ec: Escherichia coli; As: Acinetobacter sp.; Ca: Candida albicans; NT: Not tested.