Published online Apr 27, 2019. doi: 10.5319/wjo.v8.i1.1
Peer-review started: June 15, 2018
First decision: August 9, 2018
Revised: January 23, 2019
Accepted: March 15, 2019
Article in press: March 16, 2019
Published online: April 27, 2019
Core tip: In this editorial, we explore the role of CX3CR1 as therapeutic target in diseases, characterized by recruitment of inflammatory such as chronic rhinosinusitis and allergic rhinitis. Both diseases are chronic inflammatory diseases that affect the mucous membrane of the nose and paranasal sinuses. In this editorial, the novel role of CX3CR1 receptor in the immunopathology of chronic inflammation of the nose and paranasal sinuses will be explored with its potential role as therapeutic target in chronic nasal inflammation.