Myelofibrosis: Prognostication and cytoreductive treatment

Table 1 Score values for international prognostic scoring system and dynamic international prognostic scoring system

Parameter	Scores
	IPSS	DIPSS
Age > 65 yr	1	1
Hemoglobin < 10 g/dL	1	2
Leukocyte count > 25 × 109/L	1	1
Blast cells ≥ 1%	1	1
Constitutional symptoms	1	1

IPSS: Score 0 for low risk, score 1 for intermediate risk-1, score 2 for intermediate risk-2, score ≥ 3 for high risk; DIPSS: Score 0 for low risk, score 1-2 for intermediate risk-1, score 3-4 for intermediate risk-2, score 5-6 for high risk.

Table 2 Score values dynamic international prognostic scoring system-plus

Parameter	Score value
DIPSS intermediate-1	1
DIPSS intermediate-2	2
DIPSS high risk	3
Unfavorable cytogenetics	1
Red blood cell need	1
Platelet < 100 ×109/L	1

DIPSS-plus: Score 0 for low risk, score 1 for intermediate risk-1, score 2-3 for intermediate risk-2, score 4-6 for high risk; DIPSS: Dynamic International Prognostic scoring system-plus.