Published online Nov 6, 2013. doi: 10.5315/wjh.v2.i4.109
Revised: October 8, 2013
Accepted: October 17, 2013
Published online: November 6, 2013
Core tip: Assessment of blood group frequencies is important to evaluate the risk of alloimmunization after transfusion or pregnancy. Few documented studies have been published about the frequency of blood groups and extended phenotypes in the Congolese people in general and the consanguineous Yansi tribe in particular. This is also the case for the prevalence of glucose-6-phosphate dehydrogenase deficiency and sickle-cell trait. We show that the distribution of MNS blood groups is different in the Yansi tribe, compared to the general population. The Yansi also present with a higher frequency of medical disorders. This study may help in sensitizing the Congolese population about the medical risks associated with consanguineous unions and in building up a database of genetic diseases in the population.