Published online Nov 2, 2017. doi: 10.5314/wjd.v6.i4.52
Peer-review started: March 15, 2017
First decision: May 12, 2017
Revised: September 7, 2017
Accepted: October 15, 2017
Article in press: October 16, 2017
Published online: November 2, 2017
Core tip: The intestinal microbiome is a complex and dynamic bacterial community that plays an important role in human health. Alterations in microbiota composition have been related to different intestinal and extra-intestinal diseases such as psoriasis and rosacea. Studies have reported beneficial interactions between the human body and its microbiota and modulation through prebiotics and probiotics may prevent or resolve such diseases. Although the mechanisms for how the gut and skin communicate are not fully understood the association likely involves a complex connection between the nervous, immune, and endocrine systems as well as environmental factors.