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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Anesthesiol. Mar 27, 2016; 5(1): 15-27
Published online Mar 27, 2016. doi: 10.5313/wja.v5.i1.15
Published online Mar 27, 2016. doi: 10.5313/wja.v5.i1.15
Transcranial magnetic stimulation as a new tool to control pain perception
Emanuela Onesti, Maria Cristina Gori, Vittorio Frasca, Maurizio Inghilleri, Department of Neurology and Psychiatry, University of Rome “Sapienza”, 00185 Rome, Italy
Author contributions: Onesti E and Inghilleri M designed the research; Onesti E and Inghilleri M performed the research; Onesti E, Gori MC, Frasca V and Inghilleri M analyzed the data; Onesti E, Gori MC, Frasca V and Inghilleri M wrote the paper.
Conflict-of-interest statement: Authors declare no conflict of interest for this article.
Open-Access: This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Maurizio Inghilleri, Professor, Department of Neurology and Psychiatry, University of Rome “Sapienza”, Viale dell’Università 30, 00185 Rome, Italy. maurizio.inghilleri@uniroma1.it
Telephone: +39-06-49914120 Fax: +39-06-49914120
Received: June 27, 2015
Peer-review started: June 30, 2015
First decision: September 17, 2015
Revised: November 26, 2015
Accepted: December 13, 2015
Article in press: December 15, 2015
Published online: March 27, 2016
Peer-review started: June 30, 2015
First decision: September 17, 2015
Revised: November 26, 2015
Accepted: December 13, 2015
Article in press: December 15, 2015
Published online: March 27, 2016
Core Tip
Core tip: The high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) is emerging as a possible approach for pain relief. The HF-rTMS delivered to motor cortex modulates brain network implicated in pain processes, facilitating descending pain inhibitory mechainsms. Current data are promising, but a careful analysis of stimulation settings and maintenance treatment design are necessary.