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World J Anesthesiol. Mar 27, 2014; 3(1): 111-118
Published online Mar 27, 2014. doi: 10.5313/wja.v3.i1.111
Published online Mar 27, 2014. doi: 10.5313/wja.v3.i1.111
Acute coagulopathy of trauma: Mechanism, monitoring, management
Anusha Cherian, Bidkar Prasanna Udupi, Department of Anaesthesiology and Critical Care, Jawaharlal Institute of Post-graduate Medical Education and Research, Pondicherry 605006, India
Author contributions: Cherian A and Bidkar PU contributed equally to the manuscript.
Correspondence to: Anusha Cherian, Assistant Professor, Department of Anaesthesiology and Critical Care, Jawaharlal Institute of Post-graduate Medical Education and Research, 605006 Pondicherry, India. anushacherian@gmail.com
Telephone: +91-978-9197801 Fax: +413-227-2735
Received: November 11, 2013
Revised: January 14, 2014
Accepted: February 20, 2014
Published online: March 27, 2014
Revised: January 14, 2014
Accepted: February 20, 2014
Published online: March 27, 2014
Core Tip
Core tip: Coagulopathy associated with trauma is a poorly understood and managed complication seen in severely injured patients. Acute coagulopathy of trauma, as it is currently described is attributed to trauma shock and associated tissue hypoperfusion. The traditionally attributed causes of acidosis and hypothermia contribute to a delayed form of coagulopathy, which is now considered different from early coagulopathy. Timely and appropriate use of blood and blood products along with the management of hypotension is termed damage control resuscitation. Early treatment to reverse and prevent acidosis, hypothermia and coagulopathy is the main focus.