Morgaz J, Navarrete R, Granados MDM, Gómez-Villamandos RJ. Swine model in transplant research: Review of anaesthesia and perioperative management. World J Anesthesiol 2015; 4(3): 73-82 [DOI: 10.5313/wja.v4.i3.73]
Corresponding Author of This Article
Juan Morgaz, Professor, Department of Animal Medicine and Surgery, University of Córdoba, Campus de Rabanales, Carretera Nacional IV km, 396, 14014 Córdoba, Spain. v92moroj@uco.es
Research Domain of This Article
Anesthesiology
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Anesthesiol. Nov 27, 2015; 4(3): 73-82 Published online Nov 27, 2015. doi: 10.5313/wja.v4.i3.73
Swine model in transplant research: Review of anaesthesia and perioperative management
Juan Morgaz, Rocío Navarrete, María del Mar Granados, Rafael Jesús Gómez-Villamandos
Juan Morgaz, Rocío Navarrete, María del Mar Granados, Rafael Jesús Gómez-Villamandos, Department of Animal Medicine and Surgery, University of Córdoba, 14014 Córdoba, Spain
Author contributions: Morgaz J, Navarrete R, Granados MM and Gómez-Villamandos RJ contributed equally to this work.
Conflict-of-interest statement: None.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Juan Morgaz, Professor, Department of Animal Medicine and Surgery, University of Córdoba, Campus de Rabanales, Carretera Nacional IV km, 396, 14014 Córdoba, Spain. v92moroj@uco.es
Telephone: +34-957-212647 Fax: +34-957-211093
Received: June 22, 2015 Peer-review started: June 27, 2015 First decision: July 27, 2015 Revised: September 18, 2015 Accepted: October 16, 2015 Article in press: October 19, 2015 Published online: November 27, 2015
Abstract
Pigs are one of most common animal species to be used in biomedical models due to their many anatomical visceral similarities with humans, particularly with regards to transplantation. Despite this use, in many of the researches in which pigs are selected for transplantation, the anaesthesia used is an adaptation of human anaesthesia and presents some limitations such as a reduced analgesia a limited control in perioperative period. In this review we show some of the most important conditions in the preanaesthetic management and of swine as well as we review of anaesthetic protocols for the most common types of swine model of transplantation.
Core tip: Swine is a common model in research, especially in transplantation studies. A correct management and anaesthesia as well as knowledge of the different protocols in pigs are useful in performing these researches.
