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Copyright ©2013 Baishideng Publishing Group Co.
World J Orthop. Oct 18, 2013; 4(4): 186-197
Published online Oct 18, 2013. doi: 10.5312/wjo.v4.i4.186
Figure 1
Figure 1 Schematic representation of osteoblast involvement in hormone - stimulated bone resorption (reproduced with permission). OB: Osteoblast; PTH: Parathyroid hormone; PGE: Prostaglandin E.
Figure 2
Figure 2 Proposed participation of cells in the osteoblast lineage in the action of the bone - resorbing hormones (reproduced with permission from Ref. 39). PTH: Parathyroid hormone; PGE2: Prostaglandin E2; EGF: Epidermal growth factor.
Figure 3
Figure 3 Representation of the co-culture method that showed the contact-dependent promotion of osteoclast formation by stromal osteoblasts.
Figure 4
Figure 4 Concepts of regulation of osteoclastogenesis from the mid-1980’s until the discovery of the molecular regulation mechanisms. Three different signaling pathways converged to promote formation of osteoclasts through undefined mechanisms. IL: Interleukin; PTH: Parathyroid hormone; LIF: Leukemia inhibitory factor.