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For: Xing L, Xiu Y, Boyce BF. Osteoclast fusion and regulation by RANKL-dependent and independent factors. World J Orthop 2012; 3(12): 212-222 [PMID: 23362465 DOI: 10.5312/wjo.v3.i12.212]
URL: https://www.wjgnet.com/2218-5836/full/v3/i12/212.htm
Number Citing Articles
1
Ju Hee Oh, Jae Yoon Lee, Jin Hyeong Park, Jeong Hyeon No, Na Kyung Lee. Obatoclax Regulates the Proliferation and Fusion of Osteoclast Precursors through the Inhibition of ERK Activation by RANKL. Molecules and Cells 2015; 38(3) doi: 10.14348/molcells.2015.2340
2
Luz M. Castillo, Carlos A. Guerrero, Orlando Acosta. Expression of typical osteoclast markers by PBMCs after PEG-induced fusion as a model for studying osteoclast differentiation. Journal of Molecular Histology 2017; 48(3) doi: 10.1007/s10735-017-9717-4
3
Deborah L. Galson, G. David Roodman. Pathobiology of Paget's Disease of Bone. Journal of Bone Metabolism 2014; 21(2) doi: 10.11005/jbm.2014.21.2.85
4
X. Li, M. Li, J. Lu, Y. Hu, L. Cui, D. Zhang, Y. Yang. Age-related effects on osteoclastic activities after orthodontic tooth movement. Bone & Joint Research 2016; 5(10) doi: 10.1302/2046-3758.510.BJR-2016-0004.R2
5
Su Young Kim, Hwoe Gyeong Ok, Christof Birkenmaier, Kyung Hoon Kim. Can denosumab be a substitute, competitor, or complement to bisphosphonates?. The Korean Journal of Pain 2017; 30(2) doi: 10.3344/kjp.2017.30.2.86
6
7
Lena Willkomm, Wilhelm Bloch. Cell Fusion. Methods in Molecular Biology 2015; 1313 doi: 10.1007/978-1-4939-2703-6_1
8
Hyo Jeong Kim, Youngkyun Lee. Endogenous Collagenases Regulate Osteoclast Fusion. Biomolecules 2020; 10(5) doi: 10.3390/biom10050705
9
Sharon Russo, Federica Scotto di Carlo, Fernando Gianfrancesco. The Osteoclast Traces the Route to Bone Tumors and Metastases. Frontiers in Cell and Developmental Biology 2022; 10 doi: 10.3389/fcell.2022.886305
10
Nicola Alesi, Julia F. Charles, Mary C. Nakamura. Osteoporosis. Contemporary Endocrinology 2020;  doi: 10.1007/978-3-319-69287-6_2
11
Amélie E. Coudert, François Redelsperger, Yasmine Chabbi-Achengli, Cécile Vernochet, Caroline Marty, Xavier Decrouy, Thierry Heidmann, Marie-Christine de Vernejoul, Anne Dupressoir. Role of the captured retroviral envelope syncytin-B gene in the fusion of osteoclast and giant cell precursors and in bone resorption, analyzed ex vivo and in vivo in syncytin-B knockout mice. Bone Reports 2019; 11 doi: 10.1016/j.bonr.2019.100214
12
Shusil K. Pandit, Bart Westendorp, Alain de Bruin. Physiological significance of polyploidization in mammalian cells. Trends in Cell Biology 2013; 23(11) doi: 10.1016/j.tcb.2013.06.002
13
Hongyan Zhao, Jianhong Gu, Nannan Dai, Qian Gao, Dong Wang, Ruilong Song, Wei Liu, Yan Yuan, Jianchun Bian, Xuezhong Liu, Zongping Liu. Osteoprotegerin exposure at different stages of osteoclastogenesis differentially affects osteoclast formation and function. Cytotechnology 2016; 68(4) doi: 10.1007/s10616-015-9892-7
14
Timofey O. Klyucherev, Maria A. Peshkova, Maria D. Yurkanova, Nastasia V. Kosheleva, Andrey A. Svistunov, Xing-Jie Liang, Peter S. Timashev. Advances in Regenerative Therapies for Inflammatory Arthritis: Exploring the Potential of Mesenchymal Stem Cells and Extracellular Vesicles. International Journal of Molecular Sciences 2025; 26(12) doi: 10.3390/ijms26125766
15
Maria-Bernadette Madel, Lidia Ibáñez, Abdelilah Wakkach, Teun J. de Vries, Anna Teti, Florence Apparailly, Claudine Blin-Wakkach. Immune Function and Diversity of Osteoclasts in Normal and Pathological Conditions. Frontiers in Immunology 2019; 10 doi: 10.3389/fimmu.2019.01408
16
Tomoko Matsuda, Ayaka Fujita, Masayuki Hara, Masahiro Nishio, Hayato Umekawa. Tea Extract Modulates the Expression of DC-STAMP mRNA in RAW264.7 Cells. Food Science and Technology Research 2015; 21(6) doi: 10.3136/fstr.21.869
17
Chengcheng Zhang, Ce Dou, Jianzhong Xu, Shiwu Dong. DC‐STAMP, the Key Fusion‐Mediating Molecule in Osteoclastogenesis. Journal of Cellular Physiology 2014; 229(10) doi: 10.1002/jcp.24553
18
19
Archana Sanjay, Julia F. Charles. Encyclopedia of Bone Biology. 2020;  doi: 10.1016/B978-0-12-801238-3.11161-4
20
Sung-Jin Bae, Min Wook Shin, Taekwon Son, Hye Shin Lee, Ji Soo Chae, Sejin Jeon, Goo Taeg Oh, Kyu-Won Kim. Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts. Experimental & Molecular Medicine 2019; 51(1) doi: 10.1038/s12276-018-0201-3
21
Rabia Islam, Han‐Sol Bae, Won‐Joon Yoon, Kyung‐Mi Woo, Jeong‐Hwa Baek, Hong‐Hee Kim, Takafumi Uchida, Hyun‐Mo Ryoo. Pin1 Regulates Osteoclast Fusion Through Suppression of the Master Regulator of Cell Fusion DC‐STAMP. Journal of Cellular Physiology 2014; 229(12) doi: 10.1002/jcp.24679
22
Mei Chen, Dinusha Rajapakse, Monika Fraczek, Chang Luo, John V. Forrester, Heping Xu. Retinal pigment epithelial cell multinucleation in the aging eye - a mechanism to repair damage and maintain homoeostasis. Aging Cell 2016; 15(3) doi: 10.1111/acel.12447
23
Daniela M. Sousa, Francisco Conceição, Diana I. Silva, Luís Leitão, Estrela Neto, Cecília J. Alves, Inês S. Alencastre, Herbert Herzog, Paulo Aguiar, Meriem Lamghari. Ablation of Y1 receptor impairs osteoclast bone-resorbing activity. Scientific Reports 2016; 6(1) doi: 10.1038/srep33470
24
Noreen Mumtaz, Marijke Koedam, Johannes P. T. M. van Leeuwen, Marion P. G. Koopmans, Bram C. J. van der Eerden, Barry Rockx. Zika virus infects human osteoclasts and blocks differentiation and bone resorption. Emerging Microbes & Infections 2022; 11(1) doi: 10.1080/22221751.2022.2086069
25
Yu Wang, Guangyu Dong, Hyeran Helen Jeon, Mohamad Elazizi, Lan B La, Alhassan Hameedaldeen, E Xiao, Chen Tian, Sarah Alsadun, Yongwon Choi, Dana T Graves. FOXO1 Mediates RANKL-Induced Osteoclast Formation and Activity. The Journal of Immunology 2015; 194(6) doi: 10.4049/jimmunol.1402211
26
Deborah L. Galson, Quanhong Sun, G. David Roodman. Advances in Pathobiology and Management of Paget's Disease of Bone. 2016;  doi: 10.1016/B978-0-12-805083-5.00004-X
27
Satoru Shindo, Shin Nakamura, Avery Hawthorne, Alireza Heidari, Maria Rita Pastore, Motoki Okamoto, Maiko Suzuki, Manuel Salinas, Takumi Memida, Dmitriy Minond, Alexander Bontempo, Mark Cayabyab, Yingzi Yang, Janet L Crane, Maria Hernandez, Saynur Vardar, Patrick Hardigan, Xiaozhe Han, Steven Kaltman, Toshihisa Kawai. Piezo1 protects against inflammatory bone loss via a unique Ca2+-independent mechanism in osteoclasts. Frontiers in Immunology 2025; 16 doi: 10.3389/fimmu.2025.1661538
28
Mohammad Ahsanul Akbar, David Nardo, Mong-Jen Chen, Ahmed S. Elshikha, Rubina Ahamed, Eslam M. Elsayed, Claire Bigot, L. Shannon Holliday, Sihong Song. α-1 Antitrypsin Inhibits RANKL-induced Osteoclast Formation and Functions. Molecular Medicine 2017; 23(1) doi: 10.2119/molmed.2016.00170
29
W. Wisitrasameewong, M. Kajiya, A. Movila, S. Rittling, T. Ishii, M. Suzuki, S. Matsuda, Y. Mazda, M.R. Torruella, M.M. Azuma, K. Egashira, M.O. Freire, H. Sasaki, C.Y. Wang, X. Han, M.A. Taubman, T. Kawai. DC-STAMP Is an Osteoclast Fusogen Engaged in Periodontal Bone Resorption. Journal of Dental Research 2017; 96(6) doi: 10.1177/0022034517690490
30
Simon Gemble, Renata Basto. CHRONOCRISIS: When Cell Cycle Asynchrony Generates DNA Damage in Polyploid Cells. BioEssays 2020; 42(10) doi: 10.1002/bies.202000105
31
Alaleh Foroozandehfar, Jaden L. Petersen, Molly Kozminsky. Investigating Precursor Spatial Organization in Osteoclastogenesis Using DNA-Directed Cell Patterning. ACS Applied Bio Materials 2026; 9(19) doi: 10.1021/acsabm.6c01241
32
Hyunsoo Kim, Matthew C. Walsh, Noriko Takegahara, Sarah A. Middleton, Hong-In Shin, Junhyong Kim, Yongwon Choi. The purinergic receptor P2X5 regulates inflammasome activity and hyper-multinucleation of murine osteoclasts. Scientific Reports 2017; 7(1) doi: 10.1038/s41598-017-00139-2
33
Anne-Sofie Hobolt-Pedersen, Jean-Marie Delaissé, Kent Søe. Osteoclast Fusion is Based on Heterogeneity Between Fusion Partners. Calcified Tissue International 2014; 95(1) doi: 10.1007/s00223-014-9864-5
34
Jiang Wang, Bo Wang, Xin Lv, Lei Wang. NIK inhibitor impairs chronic periodontitis via suppressing non-canonical NF-κB and osteoclastogenesis. Pathogens and Disease 2020; 78(7) doi: 10.1093/femspd/ftaa045
35
Jule Taubmann, Brenda Krishnacoumar, Christina Böhm, Maria Faas, Dorothea I. H. Müller, Susanne Adam, Cornelia Stoll, Martin Böttcher, Dimitrios Mougiakakos, Uwe Sonnewald, Jörg Hofmann, Georg Schett, Gerhard Krönke, Carina Scholtysek. Metabolic reprogramming of osteoclasts represents a therapeutic target during the treatment of osteoporosis. Scientific Reports 2020; 10(1) doi: 10.1038/s41598-020-77892-4
36
Jinkyung Lee, Sun-Hee Ahn, Zhihao Chen, Sohi Kang, Dong Kyu Choi, Changjong Moon, Sang Hyun Min, Byung-Ju Park, Tae-Hoon Lee. N-[2-(4-Acetyl-1-Piperazinyl)Phenyl]-2-(3-Methylphenoxy)Acetamide (NAPMA) Inhibits Osteoclast Differentiation and Protects against Ovariectomy-Induced Osteoporosis. Molecules 2020; 25(20) doi: 10.3390/molecules25204855
37
Kaung Htike, Kunihiro Yoshida, Takanori Eguchi, Katsuki Takebe, Xueming Li, Yaxin Qu, Eiko Sakai, Takayuki Tsukuba, Kuniaki Okamoto. Herbal medicine Ninjinyoeito inhibits RANKL-induced osteoclast differentiation and bone resorption activity by regulating NF-κB and MAPK pathway. Journal of Oral Biosciences 2024; 66(4) doi: 10.1016/j.job.2024.09.007
38
Srinivas V. Koduru, Ben-hua Sun, Joanne M. Walker, Meiling Zhu, Christine Simpson, Madhav Dhodapkar, Karl L. Insogna. The contribution of cross-talk between the cell-surface proteins CD36 and CD47–TSP-1 in osteoclast formation and function. Journal of Biological Chemistry 2018; 293(39) doi: 10.1074/jbc.RA117.000633
39
Tian-yang Liu, Ling-ling Zhou, Cong Zhou, Zhang-pu Liu, Chen Chen, Zhe Feng, Xue-ping Zhou. Inhibition mechanism of Qingluo Tongbi Granule (清络通痹颗粒) on osteoclast differentiation induced by synovial fibroblast and monocytes co-culture in adjuvant-induced arthritic rats. Chinese Journal of Integrative Medicine 2015; 21(4) doi: 10.1007/s11655-014-1839-x
40
Shi-qiang Wei, chaoyang Guo, Zhi-jun Lu, Fei-xiang Lin. From acute infection to chronic osteoimmune remodeling: immunopathogenesis and precision immunotherapeutic strategies in osteomyelitis. International Immunopharmacology 2026; 181 doi: 10.1016/j.intimp.2026.116669
41
Suk-Gyun Park, Jung-Woo Kim, Ju Han Song, Seung-Hee Kwon, Sin-Hye Oh, Xianyu Piao, Zhao Wang, Je-Hwang Ryu, Nacksung Kim, Ok-Su Kim, Jeong-Tae Koh. The microbial metabolite imidazole propionate dysregulates bone homeostasis by inhibiting AMP-activated protein kinase (AMPK) signaling. Communications Biology 2024; 7(1) doi: 10.1038/s42003-024-07316-w
42
Qi Xiong, Lihai Zhang, Lingli Xin, Yanpan Gao, Ye Peng, Peifu Tang, Wei Ge. Proteomic study of different culture medium serum volume fractions on RANKL-dependent RAW264.7 cells differentiating into osteoclasts. Proteome Science 2015; 13(1) doi: 10.1186/s12953-015-0073-6
43
Cyro José de Almeida Guardiola, Juliana Trindade Clemente-Napimoga, Elizabeth Ferreira Martinez, Henrique Balassini Abdalla, Daiane Cristina Peruzzo, Júlio César Joly, Marcelo Henrique Napimoga. DC-STAMP and TACE Levels are Higher in Patients with Periodontitis. Brazilian Dental Journal 2020; 31(2) doi: 10.1590/0103-6440202002939
44
Suguru Ito, Akihiro Ohmi, Akiyo Sakamiya, Takeo Yano, Katsuzumi Okumura, Norihiro Nishimura, Kazuhiro Kagontani. Ginger hexane extract suppresses RANKL-induced osteoclast differentiation. Bioscience, Biotechnology, and Biochemistry 2016; 80(4) doi: 10.1080/09168451.2015.1127133
45
Yuanliang Xue, Chuanliang Zhao, Tao Liu. Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) accelerates osteoclast formation by regulating signal transducer and activator of transcription 3 (STAT3) signalling. Bioengineered 2022; 13(2) doi: 10.1080/21655979.2021.2024333
46
Hyunsoo Kim, Kyunghee Lee, Jin Man Kim, Mi Yeong Kim, Jae-Ryong Kim, Han-Woong Lee, Youn Wook Chung, Hong-In Shin, Taesoo Kim, Eui-Soon Park, Jaerang Rho, Seoung Hoon Lee, Nacksung Kim, Soo Young Lee, Yongwon Choi, Daewon Jeong. Selenoprotein W ensures physiological bone remodeling by preventing hyperactivity of osteoclasts. Nature Communications 2021; 12(1) doi: 10.1038/s41467-021-22565-7
47
Shahrzad Rafiei, Svetlana V Komarova. Molecular Signaling Pathways Mediating Osteoclastogenesis Induced by Prostate Cancer Cells. BMC Cancer 2013; 13(1) doi: 10.1186/1471-2407-13-605
48
Shangfu Li, Bu Yang, Dian Teguh, Lin Zhou, Jiake Xu, Limin Rong. Amyloid β Peptide Enhances RANKL-Induced Osteoclast Activation through NF-κB, ERK, and Calcium Oscillation Signaling. International Journal of Molecular Sciences 2016; 17(10) doi: 10.3390/ijms17101683
49
In Soon Kang, Chaekyun Kim. NADPH oxidase gp91phox contributes to RANKL-induced osteoclast differentiation by upregulating NFATc1. Scientific Reports 2016; 6(1) doi: 10.1038/srep38014
50
Mitsuhiko Nishimi, Koichi Nakamura, Akina Hisada, Kazuki Endo, Shuya Ushimura, Yoshitaka Yoshimura, Yasutaka Yawaka. Effects of N-acetylcysteine on root resorption after tooth replantation. Pediatric Dental Journal 2020; 30(2) doi: 10.1016/j.pdj.2020.05.002
51
Takenobu Ishii, Montserrat Ruiz‐Torruella, Atsushi Ikeda, Satoru Shindo, Alexandru Movila, Hani Mawardi, Abdullah Albassam, Rayyan A. Kayal, Ayman A. Al‐Dharrab, Kenji Egashira, Wichaya Wisitrasameewong, Kenta Yamamoto, Abdulghani I. Mira, Kenji Sueishi, Xiaozhe Han, Martin A. Taubman, Takeshi Miyamoto, Toshihisa Kawai. OC‐STAMP promotes osteoclast fusion for pathogenic bone resorption in periodontitis via up‐regulation of permissive fusogen CD9. The FASEB Journal 2018; 32(7) doi: 10.1096/fj.201701424R
52
Francesca Zito, Nadia Lampiasi, Igor Kireev, Roberta Russo. United we stand: Adhesion and molecular mechanisms driving cell fusion across species. European Journal of Cell Biology 2016; 95(12) doi: 10.1016/j.ejcb.2016.09.002
53
Xinhong Liu, Jian‐Bo Fan, Jing Hu, Fang Li, Ruokun Yi, Fang Tan, Xin Zhao. Lactobacillus Fermentum ZS40 prevents secondary osteoporosis in Wistar Rat. Food Science & Nutrition 2020; 8(9) doi: 10.1002/fsn3.1824
54
Santosh K. Verma, Leonid V. Chernomordik, Kamran Melikov. An improved metrics for osteoclast multinucleation. Scientific Reports 2018; 8(1) doi: 10.1038/s41598-018-20031-x
55
Won-Seok Lee, Eun-Gyeong Lee, Myung-Soon Sung, Yun-Jung Choi, Wan-Hee Yoo. Atorvastatin inhibits osteoclast differentiation by suppressing NF-κB and MAPK signaling during IL-1β-induced osteoclastogenesis . The Korean Journal of Internal Medicine 2018; 33(2) doi: 10.3904/kjim.2015.244
56
Gali Guterman‐Ram, Milena Pesic, Ayelet Orenbuch, Tal Czeiger, Anastasia Aflalo, Noam Levaot. Dual‐specificity tyrosine phosphorylation‐regulated kinase 2 regulates osteoclast fusion in a cell heterotypic manner. Journal of Cellular Physiology 2018; 233(1) doi: 10.1002/jcp.25922
57
Chaoquan Tian, Weijia Sun, Tao Yu, Shuai Guo, Yiqing Zhang, Shuang Li, Jiaqi He, Mingqi Yu, Lingkang Wu, Wenyi Mei, Yuheng Li, Zhenjiang Zhao, Lili Zhu, Yanyan Diao, Honglin Li, Yingxian Li, Shiliang Li. Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α1-Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents. Journal of Medicinal Chemistry 2025; 68(16) doi: 10.1021/acs.jmedchem.5c01408
58
Edwin Manrique, Luz M. Castillo, Oswaldo Lazala, Carlos A. Guerrero, Orlando Acosta. Bone resorptive activity of human peripheral blood mononuclear cells after fusion with polyethylene glycol. Journal of Bone and Mineral Metabolism 2017; 35(2) doi: 10.1007/s00774-016-0744-0
59
Zi’ang Hu, Yilei Chen, Lijiang Song, Jasper H. N. Yik, Dominik R. Haudenschild, Shunwu Fan. Flavopiridol Protects Bone Tissue by Attenuating RANKL Induced Osteoclast Formation. Frontiers in Pharmacology 2018; 9 doi: 10.3389/fphar.2018.00174
60
Jungeun Yu, Lauren Schilling, Tabitha Eller, Ernesto Canalis. Hairy and enhancer of split 1 is a primary effector of NOTCH2 signaling and induces osteoclast differentiation and function. Journal of Biological Chemistry 2021; 297(6) doi: 10.1016/j.jbc.2021.101376
61
Zhihao Chen, Alessandra Marie Encarnacion, Robin Prakash Sirvin Rajan, Hongyuan Yao, Sunwoo Lee, Eunae Kim, Tae-Hoon Lee. Discovery of a novel homoisoflavonoid derivative 5g for anti-osteoclastic bone loss via targeting FGFR1. European Journal of Medicinal Chemistry 2024; 270 doi: 10.1016/j.ejmech.2024.116335
62
Noam Levaot, Aner Ottolenghi, Mati Mann, Gali Guterman-Ram, Zvi Kam, Benjamin Geiger. Osteoclast fusion is initiated by a small subset of RANKL-stimulated monocyte progenitors, which can fuse to RANKL-unstimulated progenitors. Bone 2015; 79 doi: 10.1016/j.bone.2015.05.021
63
Liqing Zang, Kazuhiro Kagotani, Hiroko Nakayama, Jacky Bhagat, Yuki Fujimoto, Akihito Hayashi, Ryoji Sono, Hirotaka Katsuzaki, Norihiro Nishimura, Yasuhito Shimada. 10-Gingerol Suppresses Osteoclastogenesis in RAW264.7 Cells and Zebrafish Osteoporotic Scales. Frontiers in Cell and Developmental Biology 2021; 9 doi: 10.3389/fcell.2021.588093
64
Yao Hu, Wen Zhou, Chengguang Zhu, Yujie Zhou, Qiang Guo, Xiaoyu Huang, Bina Yang, Biao Ren, Lei Cheng. The Synergistic Effect of Nicotine and Staphylococcus aureus on Peri-Implant Infections. Frontiers in Bioengineering and Biotechnology 2021; 9 doi: 10.3389/fbioe.2021.658380
65
Jeyantt S. Sankaran, Bing Li, Leah Rae Donahue, Stefan Judex. Modulation of unloading-induced bone loss in mice with altered ERK signaling. Mammalian Genome 2016; 27(1-2) doi: 10.1007/s00335-015-9611-x
66
Hiroyuki Kanzaki, Alexandru Movila, Rayyan Kayal, Marcelo H. Napimoga, Kenji Egashira, Floyd Dewhirst, Hajime Sasaki, Mohammed Howait, Ayman Al-dharrab, Abdulghani Mira, Xiaozhe Han, Martin A. Taubman, Frank C. Nichols, Toshihisa Kawai. Phosphoglycerol dihydroceramide, a distinctive ceramide produced by Porphyromonas gingivalis, promotes RANKL-induced osteoclastogenesis by acting on non-muscle myosin II-A (Myh9), an osteoclast cell fusion regulatory factor. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 2017; 1862(5) doi: 10.1016/j.bbalip.2017.01.008
67
L. Huang, H. Wu, Y. Wu, F. Song, L. Zhang, Z. Li, H. Sun, C. Huang. Pcsk9 Knockout Aggravated Experimental Apical Periodontitis via LDLR. Journal of Dental Research 2022; 101(1) doi: 10.1177/00220345211015128
68
D Joshua Cohen, Cydney D Dennis, Jingyao Deng, Barbara D Boyan, Zvi Schwartz. Estradiol induces bone osteolysis in triple–negative breast cancer via its membrane–associated receptor ERα36. JBMR Plus 2024; 8(5) doi: 10.1093/jbmrpl/ziae041
69
Victor J. F. Kitano, Yoko Ohyama, Chiyomi Hayashida, Junta Ito, Mari Okayasu, Takuya Sato, Toru Ogasawara, Maki Tsujita, Akemi Kakino, Jun Shimada, Tatsuya Sawamura, Yoshiyuki Hakeda. LDL uptake-dependent phosphatidylethanolamine translocation to the cell surface promotes fusion of osteoclast-like cells. Journal of Cell Science 2020; 133(10) doi: 10.1242/jcs.243840
70
Anaïs M. J. Møller, Jean-Marie Delaissé, Jacob B. Olesen, Luisa M. Canto, Silvia R. Rogatto, Jonna S. Madsen, Kent Søe. Fusion Potential of Human Osteoclasts In Vitro Reflects Age, Menopause, and In Vivo Bone Resorption Levels of Their Donors—A Possible Involvement of DC-STAMP. International Journal of Molecular Sciences 2020; 21(17) doi: 10.3390/ijms21176368
71
Soomin Lim, Hye Jung Ihn, Ju Ang Kim, Jong-Sup Bae, Jung-Eun Kim, Yong Chul Bae, Hong-In Shin, Tae Hoon Kim, Eui Kyun Park. Suppressive effects of (-)-tubaic acid on RANKL-induced osteoclast differentiation and bone resorption. Animal Cells and Systems 2023; 27(1) doi: 10.1080/19768354.2023.2166107
72
Yi‐fei Fu, Shu‐wen Shi, Jun‐jie Wu, Zheng‐dong Yuan, Lei‐sheng Wang, Hao Nie, Zheng‐yu Zhang, Xian Wu, Yue‐chun Chen, Hui‐bo Ti, Ke‐yue Zhang, Dong Mao, Jun‐xing Ye, Xia Li, Feng‐lai Yuan. Osteoclast Secretes Stage‐Specific Key Molecules for Modulating Osteoclast–Osteoblast Communication. Journal of Cellular Physiology 2025; 240(1) doi: 10.1002/jcp.31484
73
Kent Søe, Thomas Levin Andersen, Maja Hinge, Lars Rolighed, Niels Marcussen, Jean-Marie Delaisse. Coordination of Fusion and Trafficking of Pre-osteoclasts at the Marrow–Bone Interface. Calcified Tissue International 2019; 105(4) doi: 10.1007/s00223-019-00575-4
74
Toshio Kukita, Akira Takahashi, Jing-Qi Zhang, Akiko Kukita. Cell Fusion. Methods in Molecular Biology 2015; 1313 doi: 10.1007/978-1-4939-2703-6_14
75
Monica Pata, Jean Vacher. Ostm1 Bifunctional Roles in Osteoclast Maturation: Insights From a Mouse Model Mimicking a Human OSTM1 Mutation. Journal of Bone and Mineral Research 2018; 33(5) doi: 10.1002/jbmr.3378
76
Jan Inge Øvrebø, Bruce A. Edgar. Polyploidy in tissue homeostasis and regeneration. Development 2018; 145(14) doi: 10.1242/dev.156034
77
Qiang Zhang, Xinqiao Tang, Zhong Liu, Xiaoxia Song, Dan Peng, Wei Zhu, Zhengxiao Ouyang, Wanchun Wang. Hesperetin Prevents Bone Resorption by Inhibiting RANKL-Induced Osteoclastogenesis and Jnk Mediated Irf-3/c-Jun Activation. Frontiers in Pharmacology 2018; 9 doi: 10.3389/fphar.2018.01028
78
Yibing Jia, Zili Li, Pengjie Huang, Yan Wang, Bo Yang. Mechanisms and therapeutic perspectives of mitochondrial dysfunction of macrophages in periodontitis. Frontiers in Cellular and Infection Microbiology 2025; 15 doi: 10.3389/fcimb.2025.1634909
79
Josephine Y. Fang, Zhi Yang, Bo Han. Switch of macrophage fusion competency by 3D matrices. Scientific Reports 2020; 10(1) doi: 10.1038/s41598-020-67056-9
80
Soo-Il Kim, Yun-Ho Kim, Beom Goo Kang, Min-Kyung Kang, Eun-Jung Lee, Dong Yeon Kim, Hyeongjoo Oh, Su Yeon Oh, Woojin Na, Soon Sung Lim, Young-Hee Kang. Linarin and its aglycone acacetin abrogate actin ring formation and focal contact to bone matrix of bone-resorbing osteoclasts through inhibition of αvβ3 integrin and core-linked CD44. Phytomedicine 2020; 79 doi: 10.1016/j.phymed.2020.153351
81
Ae-Jung Kim, Hankyu Lee, Hyuk Wan Ko, Seong Hee Ko, Nariyah Woo. Physiological Activity of Coffee Beans and Roasted Black Beans (Rhynchosia nulubilis) Mixture Extracts for Coffee Alternative Beverage Development. The Korean Journal of Food And Nutrition 2016; 29(2) doi: 10.9799/ksfan.2016.29.2.178
82
D. O Buev, A. M Emelin, R. V Deev. Fusion-phenomenon in normal histogenesis and in pathology: part 1. Genes & Cells 2018; 13(2) doi: 10.23868/201808014
83
Jeong-Tae Yeon, Sik-Won Choi, Byung Jun Ryu, Kwang-Jin Kim, Joo Yun Lee, Byung Jin Byun, Young-Jin Son, Seong Hwan Kim. Praeruptorin A Inhibits in Vitro Migration of Preosteoclasts and in Vivo Bone Erosion, Possibly Due to Its Potential To Target Calmodulin. Journal of Natural Products 2015; 78(4) doi: 10.1021/np501017z
84
Yunwen Peng, Hongyan Zhao, Sinan Hu, Yonggang Ma, Tao Han, Chuang Meng, Xishuai Tong, Hui Zou, Zongping Liu, Ruilong Song. Exploring the impact of osteoprotegerin on osteoclast and precursor fusion: Mechanisms and modulation by ATP. Differentiation 2024; 138 doi: 10.1016/j.diff.2024.100789
85
Hemant Joshi, Hardeep Singh Tuli, Anuj Ranjan, Abhishek Chauhan, Shafiul Haque, Seema Ramniwas, Gurpreet Kaur Bhatia, Divya Kandari. The Pharmacological Implications of Flavopiridol: An Updated Overview. Molecules 2023; 28(22) doi: 10.3390/molecules28227530
86
Emmanuela Adjei-Sowah, Indika Chandrasiri, Baixue Xiao, Yuxuan Liu, Jessica E. Ackerman, Celia Soto, Anne E. C. Nichols, Katherine Nolan, Danielle S. W. Benoit, Alayna E. Loiselle. Development of a nanoparticle-based tendon-targeting drug delivery system to pharmacologically modulate tendon healing. Science Advances 2024; 10(25) doi: 10.1126/sciadv.adn2332
87
Shuhei Kajikawa, Yuu Taguchi, Tadayoshi Hayata, Yoichi Ezura, Ryo Ueta, Sumimasa Arimura, Jun-ichiro Inoue, Masaki Noda, Yuji Yamanashi. Dok-3 and Dok-1/-2 adaptors play distinctive roles in cell fusion and proliferation during osteoclastogenesis and cooperatively protect mice from osteopenia. Biochemical and Biophysical Research Communications 2018; 498(4) doi: 10.1016/j.bbrc.2018.03.090
88
Wenmei Xiao, Guangyu Dong, Sandra Pacios, Maher Alnammary, Laura A. Barger, Yu Wang, Yingying Wu, Dana T. Graves. FOXO1 Deletion Reduces Dendritic Cell Function and Enhances Susceptibility to Periodontitis. The American Journal of Pathology 2015; 185(4) doi: 10.1016/j.ajpath.2014.12.006
89
90
Laia Mira-Pascual, Anh N. Tran, Göran Andersson, Tuomas Näreoja, Pernilla Lång. A Sub-Clone of RAW264.7-Cells Form Osteoclast-Like Cells Capable of Bone Resorption Faster than Parental RAW264.7 through Increased De Novo Expression and Nuclear Translocation of NFATc1. International Journal of Molecular Sciences 2020; 21(2) doi: 10.3390/ijms21020538
91
Benjamin Tosun, Lena Ingeborg Wolff, Astrid Houben, Stephen Nutt, Christine Hartmann. Osteoclasts and Macrophages—Their Role in Bone Marrow Cavity Formation During Mouse Embryonic Development. Journal of Bone and Mineral Research 2020; 37(9) doi: 10.1002/jbmr.4629
92
Lidia Ibáñez, Paloma Guillem-Llobat, Marta Marín, María Isabel Guillén. Connection between Mesenchymal Stem Cells Therapy and Osteoclasts in Osteoarthritis. International Journal of Molecular Sciences 2022; 23(9) doi: 10.3390/ijms23094693
93
Stuart B. Goodman, Jiri Gallo. Periprosthetic Osteolysis: Mechanisms, Prevention and Treatment. Journal of Clinical Medicine 2019; 8(12) doi: 10.3390/jcm8122091
94
95
Zhong-Hua Chen, Jun-Jie Wu, Dan-Yang Guo, Yue-Yue Li, Meng-Nan Chen, Zhen-Yu Zhang, Zheng-Dong Yuan, Kai-Wen Zhang, Wei-Wei Chen, Fan Tian, Jun-Xing Ye, Xia Li, Feng-Lai Yuan. Physiological functions of podosomes: From structure and function to therapy implications in osteoclast biology of bone resorption. Ageing Research Reviews 2023; 85 doi: 10.1016/j.arr.2023.101842
96
Kenta Yamamoto, Shin-Ichi Sawada, Satoru Shindo, Shin Nakamura, Young M. Kwon, Nazanin Kianinejad, Saynur Vardar, Maria Hernandez, Kazunari Akiyoshi, Toshihisa Kawai. Cationic Glucan Dendrimer Gel-Mediated Local Delivery of Anti-OC-STAMP-siRNA for Treatment of Pathogenic Bone Resorption. Gels 2024; 10(6) doi: 10.3390/gels10060377
97
Otto Manninen, Tero Puolakkainen, Jemina Lehto, Elina Harittu, Aki Kallonen, Marko Peura, Tiina Laitala-Leinonen, Outi Kopra, Riku Kiviranta, Anna-Elina Lehesjoki. Impaired osteoclast homeostasis in the cystatin B-deficient mouse model of progressive myoclonus epilepsy. Bone Reports 2015; 3 doi: 10.1016/j.bonr.2015.10.002
98
Liang Ren, Jing Yang, Jun Wang, Xuedong Zhou, Chengcheng Liu, Sing-Wai Wong. The Roles of FOXO1 in Periodontal Homeostasis and Disease. Journal of Immunology Research 2021; 2021 doi: 10.1155/2021/5557095
99
Rialnat A Lawal, Xichao Zhou, Kaylind Batey, Corey M Hoffman, Mary A Georger, Freddy Radtke, Matthew J Hilton, Lianping Xing, Benjamin J Frisch, Laura M Calvi. The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool. Journal of Bone and Mineral Research 2017; 32(6) doi: 10.1002/jbmr.3106
100
Yanhua Lan, Huizhi Xie, Yang Shi, Qianrui Jin, Xiaolei Zhang, Yu Wang, Zhijian Xie. NEMO‑binding domain peptide ameliorates inflammatory bone destruction in a Staphylococcus�aureus‑induced chronic osteomyelitis model. Molecular Medicine Reports 2019;  doi: 10.3892/mmr.2019.9975
101
102
Aleena Anwar, Leena Sapra, Navita Gupta, Rudra P. Ojha, Bhupendra Verma, Rupesh K. Srivastava. Fine‐tuning osteoclastogenesis: An insight into the cellular and molecular regulation of osteoclastogenesis. Journal of Cellular Physiology 2023; 238(7) doi: 10.1002/jcp.31036
103
Sevan Belian, Chiara Zurzolo. Breaking cellular boundaries: molecular mechanisms of tunneling nanotube formation and fusion. Biochemical Society Transactions 2026; 54(3) doi: 10.1042/BST20250093
104
Da-Le Yoon, Su-Yeon Park, Yong-Gun Kim, Jae-Mok Lee. Interrelation between plasma membrane calcium ATPase-1 and inflammatory mediators expression in gingival tissue depending on severity of periodontitis. Oral Biology Research 2020; 44(1) doi: 10.21851/obr.44.01.202003.23
105
Sumin Lee, Jae-Hyun Kim, Minsun Kim, Sooyeon Hong, Hoyeon Park, Eom Ji Kim, Eun-Young Kim, Chungho Lee, Youngjoo Sohn, Hyuk Sang Jung. Exploring the Anti-Osteoporotic Potential of Daucosterol: Impact on Osteoclast and Osteoblast Activities. International Journal of Molecular Sciences 2023; 24(22) doi: 10.3390/ijms242216465