Tubulocystic renal cell carcinoma with aggressive behavior-insights from molecular profiling and single-cell analysis: A case report

doi:10.5306/wjco.122878

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Oncol. Sep 24, 2026; 17(9): 122878
Published online Sep 24, 2026. doi: 10.5306/wjco.122878

Table 1 Genetic testing results

	Base alteration	Amino acid alteration	Mutation frequency (%)
Germline mutation
FH	c.1106C>G	p.P369R	69.14
Somatic mutations
AFF3	c.2800G>A	p.A934T	24.27
MDM2	c.1165A>G	p.T389A	14.29
LRP1B	c.11856T>A	p.H3952Q	13.70

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Citation: Zheng CL, Wang Z, Liu GL, Xiao HY, Xie XD, Wang ZQ, Zhang Y, Zhang J, Jiang J, Liu QL, Lan WH. Tubulocystic renal cell carcinoma with aggressive behavior-insights from molecular profiling and single-cell analysis: A case report. World J Clin Oncol 2026; 17(9): 122878
URL: https://www.wjgnet.com/2218-4333/full/v17/i9/122878.htm
DOI: https://dx.doi.org/10.5306/wjco.122878

Zheng CL, Wang Z, Liu GL, Xiao HY, Xie XD, Wang ZQ, Zhang Y, Zhang J, Jiang J, Liu QL, Lan WH. Tubulocystic renal cell carcinoma with aggressive behavior-insights from molecular profiling and single-cell analysis: A case report. World J Clin Oncol 2026; 17(9): 122878 [DOI: 10.5306/wjco.122878]

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