Novel mechanism of drug resistance to proteasome inhibitors in multiple myeloma

doi:10.5306/wjco.v10.i9.303

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Sep 24, 2019 (publication date) through May 10, 2024

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World Journal of Clinical Oncology

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2218-4333

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Sep 24, 2019; 10(9): 303-306
Published online Sep 24, 2019. doi: 10.5306/wjco.v10.i9.303

Table 1 Molecular cytogenetic classification of multiple myeloma and prognosis

Chromosomes affected (gene)	Ploidy	Prognosis	Ref.
t (11;14) (CCND3)	NH	Good	[4]
t (14;16) (c-MAF)	NH	Poor	[5]
t (4;14) (FGFR3 and NSD2)	NH/H	Poor	[6,7]
Other IgH	NH/H	Poor	[8]
Hyperdiploidy	H	Good	[9]

IgH: Immunoglobulin heavy chain; H: Hyperdiploidy; NH: Non-hyperdiploidy.

Citation: Zhou J, Chng WJ. Novel mechanism of drug resistance to proteasome inhibitors in multiple myeloma. World J Clin Oncol 2019; 10(9): 303-306
URL: https://www.wjgnet.com/2218-4333/full/v10/i9/303.htm
DOI: https://dx.doi.org/10.5306/wjco.v10.i9.303