Review
Copyright ©The Author(s) 2020.
World J Clin Oncol. Feb 24, 2020; 11(2): 53-73
Published online Feb 24, 2020. doi: 10.5306/wjco.v11.i2.53
Figure 1
Figure 1 Different cut-off levels of E of early tumor shrinkage at first tumor response assessment (6 or 8 wk). A: ≥ -10% (5 cases); B: ≥ -20% (4 cases); C: ≥ -30% (3 cases). CR: Complete response; PR: Partial response; SD: Stable disease.
Figure 2
Figure 2 Two hypothetical examples of tumor shrinkage. Example 1: Spheroid mass, symmetric (proportional) shrinkage; Example 2: Irregular mass, asymmetric shrinkage. t0: Time point baseline; t1: Time point-1; t2: Time point-2; A, B, C: Spheroid mass; X, Y, Z: Irregular mass.
Figure 3
Figure 3 Pseudoprogression. t0: Time point baseline; t1: Time point-1; t2: Time point-2; NK: Natural killer.
Figure 4
Figure 4 Waterfall, spider (spaghetti) and swimmer plot for 12 hypothetical cases. A: Waterfall; B: Spider (spaghetti); C: Swimmer. Case 8 (blue arrow with cycle) represents pseudoprogression at the 4th week. RR: Response rate; CR: Complete response; PR: Partial response; SD: Stable disease; PD: Progressive disease.