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©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. Feb 10, 2018; 9(1): 13-19
Published online Feb 10, 2018. doi: 10.5306/wjco.v9.i1.13
Published online Feb 10, 2018. doi: 10.5306/wjco.v9.i1.13
Palliative surgery for Krukenberg tumors – 12-year experience and review of the literature
Isaac Seow-En, Leonard Ming Li Ho, Department of Colorectal Surgery, Singapore General Hospital, Singapore 169608, Singapore
Gwen Hwarng, Duke-NUS Medical School, Singapore 169857, Singapore
Grace Hwei Ching Tan, Melissa Ching Ching Teo, Department of Surgical Oncology, National Cancer Centre, Singapore 169610, Singapore
Author contributions: Tan GHC and Teo MCC contributed to the study conception and design; Seow-En I, Hwarng G and Ho LML contributed to data acquisition, data analysis, interpretation and writing of the article; Tan GHC and Teo MCC contributed to editing, reviewing and final approval of the article.
Institutional review board statement: The study was reviewed and approved by the SingHealth Institutional Review Board.
Informed consent statement: Informed consent was not required for this retrospective study and all details that might disclose the identity of the subjects under study was omitted or anonymized.
Conflict-of-interest statement: All authors declare no conflict-of-interest.
Data sharing statement: Consent for data sharing was not obtained as presented data is anonymized and risk of identification is low.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Melissa Ching Ching Teo, MBBS, MMed (Surg), FRCSEd, FAMS, MPH, Senior Consultant, Head, Department of Surgical Oncology, National Cancer Centre, 11 Hospital Drive, Singapore 169610, Singapore. melissa.teo.c.c@nccs.com.sg
Telephone: +65-64368283 Fax: +65-62257559
Received: September 23, 2017
Peer-review started: September 24, 2017
First decision: November 7, 2017
Revised: November 7, 2017
Accepted: November 25, 2017
Article in press: November 25, 2017
Published online: February 10, 2018
Peer-review started: September 24, 2017
First decision: November 7, 2017
Revised: November 7, 2017
Accepted: November 25, 2017
Article in press: November 25, 2017
Published online: February 10, 2018
Core Tip
Core tip: Krukenberg tumors represent metastases to the ovary and convey a poor prognosis. By reporting our 12-year experience with palliative surgery for Krukenberg tumors and discussing the existing literature, we hope to shed light and establish best practices on the approach to management of the disease. Palliative surgery for patients with Krukenberg tumors can be performed safely in an experienced unit with acceptable complication rates. Where possible, bilateral oophorectomy should be performed to obviate the risk of the contralateral ovary developing symptomatic tumors. Appropriate selection by a multidisciplinary consensus is essential for asymptomatic patients who may benefit from prophylactic surgery.