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©2014 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Clin Oncol. May 10, 2014; 5(2): 149-155
Published online May 10, 2014. doi: 10.5306/wjco.v5.i2.149
Published online May 10, 2014. doi: 10.5306/wjco.v5.i2.149
Bone metastases: When and how lung cancer interacts with bone
Ilaria Roato, CeRMS, AO Città della Salute e della Scienza di Torino, Department of Medical Science, University of Turin, 10126 Torino, Italy
Author contributions: Roato I contributed to the conception, literature analysis, drafting and revising of this review.
Supported by Italian Ministry of Health: Ricerca Sanitaria Finalizzata e Giovani Ricercatori 2009, No. GR 2009-1584485
Correspondence to: Ilaria Roato, PhD, CeRMS, AO Città della Salute e della Scienza di Torino, Department of Medical Science, University of Turin, Via Santena 5, 10126 Torino, Italy. roato78@libero.it
Telephone: +39-11-6334672 Fax: +39-11-6334672
Received: December 27, 2013
Revised: February 21, 2014
Accepted: March 17, 2014
Published online: May 10, 2014
Revised: February 21, 2014
Accepted: March 17, 2014
Published online: May 10, 2014
Core Tip
Core tip: This review reports current knowledge on the cross-talk among lung tumor cells, the bone microenvironment, and the immune system, that lead to bone metastasis.