Squamous cell carcinoma of the skin: Emerging need for novel biomarkers

doi:10.5306/wjco.v4.i4.85

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Nov 10, 2013 (publication date) through Apr 24, 2024

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World Journal of Clinical Oncology

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Oncol. Nov 10, 2013; 4(4): 85-90
Published online Nov 10, 2013. doi: 10.5306/wjco.v4.i4.85

Squamous cell carcinoma of the skin: Emerging need for novel biomarkers

Atte Kivisaari, Veli-Matti Kähäri

Atte Kivisaari, Veli-Matti Kähäri, Department of Dermatology and Venereology, Turku University Hospital, University of Turku, FI-20521 Turku, Finland

Atte Kivisaari, Veli-Matti Kähäri, MediCity Research Laboratory, University of Turku, FI-20521 Turku, Finland

Author contributions: Kivisaari A and Kähäri VM contributed to the writing of this manuscript.

Supported by The Academy of Finland, project 137687; the Finnish Cancer Research Foundation, Sigrid Jusélius Foundation, Turku University Hospital EVO grant, project 13336; and by personal grant to Kivisaari A from Finnish Medical Foundation

Correspondence to: Veli-Matti Kähäri, MD, PhD, Professor, Department of Dermatology, Turku University Hospital, University of Turku, FI-20521 Turku,Finland. veli-matti.kahari@utu.fi

Telephone: +358-2-3131600 Fax: +358-2-3131610

Received: March 11, 2013
Revised: June 26, 2013
Accepted: July 17, 2013
Published online: November 10, 2013

Core Tip

Core tip: Several molecular markers for progression of cutaneous squamous cell carcinoma (cSCC) have been identified, but a clinically useful panel of biomarkers is still not available. Further studies are required to determine whether prognostic cSCC biomarker panel can be incorporated into clinical practice. In the meantime, while waiting for novel diagnostic and prognostic tools, clinicians must actively advocate public awareness on skin protection against excessive sun exposure in order to lower the increasing incidence of cSCC.