Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Oncol. May 24, 2019; 10(5): 213-221
Published online May 24, 2019. doi: 10.5306/wjco.v10.i5.213
Published online May 24, 2019. doi: 10.5306/wjco.v10.i5.213
Clear cell sarcoma in unusual sites mimicking metastatic melanoma
Ifeyinwa E Obiorah, Metin Ozdemirli, Department of Pathology, Medstar Georgetown University Hospital, Washington, DC 20007, United States
Author contributions: Obiorah IE and Ozdemirli M contributed to the acquisition of data and the writing and revision of the manuscript.
Informed consent statement: Consent was obtained from the patients prior to study enrollment.
Conflict-of-interest statement: Both authors declare that they have no conflicts of interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ifeyinwa E Obiorah, MD, PhD, Staff Physician, Department of Pathology, Medstar Georgetown University Hospital, 3800 Reservoir Road NW, Washington, DC 20007, United States. ifeyinwa.e.obiorah@gunet.georgetown.edu
Telephone: +1-202-3843639 Fax: +1-202-6878935
Received: January 25, 2019
Peer-review started: January 25, 2019
First decision: January 29, 2019
Revised: February 15, 2019
Accepted: March 16, 2019
Article in press: March 16, 2019
Published online: May 24, 2019
Peer-review started: January 25, 2019
First decision: January 29, 2019
Revised: February 15, 2019
Accepted: March 16, 2019
Article in press: March 16, 2019
Published online: May 24, 2019
Core Tip
Core tip: The diagnosis and management of clear cell sarcoma can be a clinical dilemma. Recognition of the clinicopathologic pattern and differentiating it from malignant melanoma can prevent misdiagnosis. This case report not only represents the first reported occurrence of clear cell sarcoma in the submandibular gland in the literature but also identifies another unusual location of involvement, the thoracic spine. It is important to promptly recognize this disease entity because early treatment is necessary to prevent fatal consequences.