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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Fibroblast growth factor receptor 4 single nucleotide polymorphism Gly388Arg in head and neck carcinomas
Eva Wimmer, Stephan Ihrler, Olivier Gires, Sylvia Streit, Wolfgang Issing, Christoph Bergmann
Eva Wimmer, Olivier Gires, Wolfgang Issing, Christoph Bergmann, Department of Otorhinolaryngology, Ludwig-Maximilians-University, Munich 81377, Germany
Stephan Ihrler, Institute of Pathology, Ludwig-Maximilians-University, Munich 80337, Germany
Olivier Gires, Clinical Cooperation Group Personalized Radiotherapy of Head and Neck Tumors, Neuherberg 71083, Germany
Sylvia Streit, Department of Molecular Biology, Max-Planck-Institute for Biochemistry, Planegg 82152, Germany
Wolfgang Issing, ENT Department, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, United Kingdom
Christoph Bergmann, Department of Otorhinolaryngology, University of Duisburg-Essen, Essen 45147, Germany
Author contributions: Wimmer E performed the majority of experiments, analyzed the data and wrote the paper, Ihrler S conducted analysis of histology, Gires O helped writing the paper, Streit S conducted experiments, Issing W designed and coordinated the research; Bergmann C performed experiments, analyzed the data, conducted statistical analysis and helped the write the paper.
Institutional review board statement: The study was reviewed and approved by the Ludwig-Maximilian University Institutional Review Board.
Institutional animal care and use committee statement: Not applicable to this study.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
Data sharing statement: Dataset available from the corresponding author at Christoph.bergmann@uk-essen.de.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Christoph Bergmann, MD, PhD, Assistant Professor, Senior Lecturer, Surgeon, Department of Otorhinolaryngology, University of Duisburg-Essen, Hufelandstr. 55, Essen 45147, Germany. christoph.bergmann@uk-essen.de
Telephone: +49-151-40512955
Received: December 6, 2018
Peer-review started: December 6, 2018
First decision: December 30, 2018
Revised: January 16, 2019
Accepted: January 30, 2019
Article in press: January 30, 2019
Published online: March 24, 2019
