Case Report
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World J Clin Oncol. Feb 10, 2014; 5(1): 28-32
Published online Feb 10, 2014. doi: 10.5306/wjco.v5.i1.28
Clitoris metastasis from a retroperitoneal leiomyosarcoma: A case report
Suna Cokmert, Lutfiye Demir, Murat Akyol, Ibrahim Vedat Bayoglu, Alper Can, Ilkay Tugba Unek, Filiz Aka Bolat
Suna Cokmert, Lutfiye Demir, Murat Akyol, Ibrahim Vedat Bayoglu, Alper Can, Department of Medical Oncology, Izmir Ataturk Training and Research Hospital, 35170 Izmir, Turkey
Ilkay Tugba Unek, Department of Medical Oncology, Tepecik Training and Research Hospital, 35460 Tepecik, Turkey
Filiz Aka Bolat, Department of Pathology, Adana Baskent University, 01250 Adana, Turkey
Author contributions: Cokmert S and Demir L designed the report; Can A, Akyol M and Bayoglu IV were attending doctors for the patient; Bolat FA performed pathological examinations; Cokmert S and Unek IT organized the report; Cokmert S wrote paper.
Correspondence to: Suna Cokmert, MD, PhD, Department of Medical Oncology, Izmir Ataturk Training and Research Hospital, Basin Site, 35170 Izmir, Turkey. sunacok@gmail.com
Telephone: +90-232-3867070 Fax: +90-232-3867071
Received: September 9, 2013
Revised: November 5, 2013
Accepted: November 18, 2013
Published online: February 10, 2014
Abstract

Leiomyosarcoma is a rare form of cancer commonly found in the retroperitoneum, uterus, stomach, small intestine and vascular tissue. Surgery with a wide margin of resection is the most effective treatment. Nevertheless, metastasis is common and generally occurs within the first 3 years. The liver and lungs are the most common sites of metastasis in leiomyosarcoma. Other sites of metastasis include bone, spleen, soft tissues and brain. Metastatic tumours of the clitoris are extremely rare. As cited in the literature, the most common cancers that metastasize to the clitoris are breast, bladder, renal and gastric. Here, we report a case of a clitoral mass in a 64-year-old woman who received an operation for retroperitoneal leiomyosarcoma 4 years prior. Mass resection was performed. The pathological diagnosis was a leiomyosarcoma metastasis. The patient also presented with brain and lung metastases at the time of the clitoral metastasis. This is the first case of clitoral and brain metastases originating from a retroperitoneal leiomyosarcoma.

Keywords: Leiomyosarcoma, Clitoris, Brain, Lung, Metastasis

Core tip: This is the first case of a clitoral metastasis originating from a retroperitoneal leiomyosarcoma. Furthermore, this report highlights the importance of atypical metastases in leiomyosarcomas.