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World J Clin Oncol. Jan 10, 2011; 2(1): 64-72
Published online Jan 10, 2011. doi: 10.5306/wjco.v2.i1.64
Optical mammography: Diffuse optical imaging of breast cancer
Kijoon Lee
Kijoon Lee, Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637457, Singapore
Author contributions: Lee K is the sole author of this review paper.
Correspondence to: Dr. Kijoon Lee, PhD, Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, 70 Nanyang, Singapore 637457, Singapore. kjlee@ntu.edu.sg
Telephone: + 65-63162894   Fax: + 65-67911761
Received: August 10, 2010
Revised: November 1, 2010
Accepted: November 8, 2010
Published online: January 10, 2011
Abstract

Existing imaging modalities for breast cancer screening, diagnosis and therapy monitoring, namely X-ray mammography and magnetic resonance imaging, have been proven to have limitations. Diffuse optical imaging is a set of non-invasive imaging modalities that use near-infrared light, which can be an alternative, if not replacement, to those existing modalities. This review covers the background knowledge, recent clinical outcome, and future outlook of this newly emerging medical imaging modality.

Keywords: Diffuse optical imaging, Diffuse optical spectroscopy, Breast cancer, Optical mammography, Therapy monitoring