Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Nov 6, 2016; 7(4): 503-512
Published online Nov 6, 2016. doi: 10.4292/wjgpt.v7.i4.503
Logical hypothesis: Low FODMAP diet to prevent diverticulitis
Yoshiharu Uno, Jennifer C van Velkinburgh
Yoshiharu Uno, Office Uno Column (Medical Science Publisher), Onoe-Cho, Hyogo 675-0025, Japan
Jennifer C van Velkinburgh, van Velkinburgh Initiative for Collaboratory Biomedical Research, Santa Fe, NM 87501, United States
Author contributions: Uno Y contributed to creation of theory, reference collection, and creation of the table and figures; Uno Y and van Velkinburgh JC contributed equally to the writing of the manuscript.
Conflict-of-interest statement: Uno Y was granted a trademark of low FODMAP diet from the Japan Patent Office. van Velkinburgh JC declares no conflicts of interest in relation to the publication of this review.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Yoshiharu Uno, MD, PhD, Office Uno Column (Medical Science Publisher), Onoe-Cho, Yota 419-2, Hyogo 675-0025, Japan.
Telephone: +81-79-4394697 Fax: +81-79-4394697
Received: April 27, 2016
Peer-review started: April 28, 2016
First decision: July 4, 2016
Revised: August 4, 2016
Accepted: August 15, 2016
Article in press: August 17, 2016
Published online: November 6, 2016
Core Tip

Core tip: The ongoing uncertainty of the cause(s) of diverticulitis confounds attempts to determine the validity of this therapy; however, the features of a high-fiber diet represent a logical contradiction for colon diverticulitis. Prevention of high pressure in the colon may help to avoid or correct diverticulitis, and this may be achieved by adoption of a low FODMAP diet (restriction of fermentable oligosaccharides, disaccharides, monosaccharides, and polyols).