Topic Highlight
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Pharmacol Ther. Feb 6, 2016; 7(1): 5-20
Published online Feb 6, 2016. doi: 10.4292/wjgpt.v7.i1.5
Pharmacological- and non-pharmacological therapeutic approaches in inflammatory bowel disease in adults
Gerda C Leitner, Harald Vogelsang
Gerda C Leitner, University Clinic for Blood Group Serology and Transfusion Medicine, Medical University, 1090 Vienna, Austria
Harald Vogelsang, University Clinic of Gastroenterology, 3rd Internal Medicine, Medical University, 1090 Vienna, Austria
Author contributions: Leitner GC collected the data and wrote the paper; Vogelsang H gave scientific support and revised the paper.
Conflict-of-interest statement: Authors declare no conflict of interests’ for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Gerda C Leitner, MD, University Clinic for Blood Group Serology and Transfusion Medicine, Medical University, Waehringer Guertel 18-20, 1090 Vienna, Austria.
Telephone: +43-1-4040053080 Fax: +43-1-4040075070
Received: April 29, 2015
Peer-review started: May 7, 2015
First decision: August 4, 2015
Revised: December 14, 2015
Accepted: January 8, 2016
Article in press: January 11, 2016
Published online: February 6, 2016
Core Tip

Core tip: This review describes current and future therapeutic strategies in Crohn’s disease and ulcerative colitis and outlines the most important publications in this field. It comprises surgical, medical and extracorporeal treatment options. All described treatment options are carefully reviewed regarding therapeutic effects and side effects. Extracorporeal treatment options are a potent measure to withdraw patients from steroids. Standard treatment as well as innovative therapeutic approaches, like autologous stem cell transplantation are addressed, which revealed promising results in therapy refractory patients.