Denise E Brennan, Colm O'Morain, Deirdre McNamara, Sinead M Smith, Department of Clinical Medicine, Trinity College Dublin, Trinity Centre, Tallaght University Hospital, Dublin D24, Ireland
Author contributions: McNamara D conceived the study; Brennan DE and Smith SM performed experiments, acquired and analysed data; O’Morain C and McNamara D recruited patients and collected samples; Smith SM prepared the manuscript; all authors critically reviewed the manuscript and approved the final version; Smith SM and McNamara D contributed equally.
Supported by Health Research Board, No. HRA-POR-2014-526, and No. APA-2019-030.
Institutional review board statement: The study was reviewed and approved by the Joint Research Ethics Committee of St. James’s Hospital and Tallaght University Hospital.
Conflict-of-interest statement: All authors have nothing to disclose.
Data sharing statement: No additional data are available.
: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sinead M Smith, BSc, PhD, Assistant Professor, Department of Clinical Medicine, Trinity College Dublin, Trinity Centre, Tallaght University Hospital, Tallaght, Dublin D24, Ireland. email@example.com
Received: July 23, 2021
Peer-review started: July 23, 2021
First decision: October 3, 2021
Revised: October 16, 2021
Accepted: January 14, 2022
Article in press: January 14, 2022
Published online: January 22, 2022