Update on molecular pathogenesis of Helicobacter pylori-induced gastric cancer

Figure 1 The key virulence factors involved in the pathogenicity of Helicobacter pylori infection. BabA: Blood group antigen-binding adhesion A; SabA: Sialic acid-binding adhesion A; NAP: Neutrophil activating protein; Hsp: Heat shock protein; VacA: Vacuolating cytotoxin gene A; CagA: Cytotoxin-associated gene A; T4SS: Type IV secretion system; ROS: Reactive oxygen species; IL: Interleukin; MIP: Macrophage inflammatory protein.

Figure 2 The main signaling pathways implicated in the pathogenesis of gastric cancer development by Helicobacter pylori virulence factors. This figure was created by BioRender.com (Supplementary material).