Mucosal healing in inflammatory bowel disease: Maintain or de-escalate therapy
Marcello Cintolo, Giuseppe Costantino, Walter Fries, Clinical Unit for Chronic Bowel Disorders, Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy
Socrate Pallio, Digestive Endoscopy Unit, Department of Human Pathology, University of Messina, 98125 Messina, Italy
Author contributions: Cintolo M and Fries W drafted and wrote the manuscript; Costantino G and Pallio S critically reviewed the manuscript; all authors approved the final version of the article.
Conflict-of-interest statement: Marcello Cintolo, Giuseppe Costantino and Socrate Pallio have no conflict of interests to declare. Walter Fries, MSD, AbbVie, Mundipharma advisory board; Zambon, Mundipharma: speaker fees; MSD unrestricted research grant.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Walter Fries, MD, Clinical Unit for Chronic Bowel Disorders, Department of Clinical and Experimental Medicine, University of Messina, Via Consolare Valeria, 1, 98125 Messina, Italy. firstname.lastname@example.org
Telephone: +39-090-2212380 Fax: +39-090-2213538
Received: July 29, 2015
Peer-review started: August 24, 2015
First decision: October 13, 2015
Revised: November 16, 2015
Accepted: December 7, 2015
Article in press: December 8, 2015
Published online: February 15, 2016