Published online Nov 15, 2014. doi: 10.4291/wjgp.v5.i4.384
Revised: March 19, 2014
Accepted: July 15, 2014
Published online: November 15, 2014
Core tip:Helicobacter pylori (H. pylori) is the only bacterium that has been linked to cancer to date. The efficacy of antibiotic-based eradication treatment is hampered by antibiotic resistance and side effects that may reduce patient compliance. No vaccine is currently licensed. Thus, administration of alternative compounds that may increase the efficacy of the treatment and/or reduce side effects is of particular interest. Administration of probiotics has been proposed to increase tolerability and efficacy of the H. pylori eradication treatment. The results of the most recent clinical trials seem to confirm these hypotheses.