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World J Gastrointest Pathophysiol. May 15, 2014; 5(2): 54-62
Published online May 15, 2014. doi: 10.4291/wjgp.v5.i2.54
Published online May 15, 2014. doi: 10.4291/wjgp.v5.i2.54
“Mucosal healing” in ulcerative colitis: Between clinical evidence and market suggestion
Cristiano Pagnini, Francesca Menasci, Stefano Festa, Gianenrico Rizzatti, Gianfranco Delle Fave, “Sapienza” University of Rome, Faculty of Medicine and Psychology, S. Andrea Hospital, 00189 Rome, Italy
Cristiano Pagnini, Research Center, S.Pietro Hospital, 00189 Rome, Italy
Author contributions: Pagnini C designed and wrote the paper; Menasci F, Festa S and Rizzatti G wrote the paper; Delle Fave G edited the paper.
Correspondence to: Cristiano Pagnini, MD, PhD, “Sapienza” University of Rome, Faculty of Medicine and Psychology, S. Andrea Hospital, Via di Grottarossa 1035, 00189 Rome, Italy. cristiano.pagnini@uniroma1.it
Telephone: +39-06-33779 Fax: +39-06-33776601
Received: January 16, 2014
Revised: April 4, 2014
Accepted: April 16, 2014
Published online: May 15, 2014
Revised: April 4, 2014
Accepted: April 16, 2014
Published online: May 15, 2014
Core Tip
Core tip: In recent years, the concept that the management of ulcerative colitis patients should aim to heal the mucosa rather than resolve symptoms has been decisively proposed. Herein, we review the current evidence supporting this statement and analyze the possible practical implications in the current management of ulcerative colitis patients.