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Copyright ©The Author(s) 2017.
World J Radiol. Sep 28, 2017; 9(9): 339-349
Published online Sep 28, 2017. doi: 10.4329/wjr.v9.i9.339
Table 3 Common elective premedication protocols for high-risk patients to develop iodinated contrast medium hypersensitivity reactions
ElectiveEmergency
Lasser protocolGreenberger protocol1IV protocols (in descending order of desirability)
Oral prednisone 50 mg at 13/7 and 1 h before contrast medium injectionOral methylprednisolone 32 mg at 12 and 2 h before contrast medium injection +/-Methylprednisolone sodium succinate 40 mg
OR
hydrocortisone sodium succinate 200 mg
every 4 h till examination
+ diphenhydramine 50 mg IV - 1 h
+ (oral/IM or IV) diphenhydramine 50 mg just 1 h before examination+/- (oral/IM or IV) diphenhydramine 50 mg just 1 h before examinationNo corticosteroids at all
(not preferable)
Only diphenhydramine 50 mg IV